Psychological Predictors in Colorectal Cancer Surgery Recovery

NCT ID: NCT03781193

Last Updated: 2018-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-06

Study Completion Date

2019-07-06

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is an observation pilot trial aimed to study to the association between mindfulness and other psychological factors, including both protective and risk factors, with recovery of functional ability following colorectal cancer surgery.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Preliminary evidence suggests that there are multiple variables that may influence the functional recovery following colorectal cancer surgery, some of which deal with the psychological domain. Distress and depression can negatively affect the perceptions of functional ability, while resilience and effective coping styles promote a better psychological adaptation to challenging situations. Furthermore, psychosocial prehabilitation and interventions have been proposed as a feasible and cost-effective way to positively influence the recovery after surgery in association with the Enhanced Recovery After Surgery (ERAS) protocol.

In particular, mindfulness is proved to be associated with higher quality of life in different medical conditions, including oncological patients and has been also associated with improved clinical outcomes.

The aim of the study is to investigate the association of mindfulness and other psychological predictors with functional and quality of life outcomes in patients undergoing colorectal surgery for oncological condition.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Colorectal Cancer

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

mindfulness Psychological predictors Colorectal surgery ERAS

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Questionnaires administration

Psychological and quality of life questionnaires

Intervention Type OTHER

Five Facet Mindfulness Questionnaire (FFMQ)

FFMQ is a 39-item measure consisting of five subscales (observing, describing, acting with awareness, non-judging of inner experience, and non-reactivity to inner experience).

Intervention Type OTHER

Langer Mindfulness Scale (LMS)

The LMS Tis a 21-item questionnaire, assessing four domains associated with mindful thinking: novelty-seeking, engagement, novelty producing, and flexibility.

Intervention Type OTHER

Cognitive Flexibility Scale (CFS)

The CFS is 12-item self-report test assessing awareness.

Intervention Type OTHER

Life Orientation Test (LOT)

The LOT is a 10-item, self-administered scale assessing generalized expectancies for positive versus negative outcomes.

Intervention Type OTHER

Mini Locus of Control test (MLS)

The MLS is a 6-item questionnaire that includes 3 factors : chance, powerful others, and internality.

Intervention Type OTHER

Hospital Anxiety and Depression Scale (HADS)

The HADS is a 14-items rated on a four-point Likert scale. The questionnaire was designed to screen for the presence and severity of depression (HADS-D) and anxiety (HADS-A) in people with a physical symptomatology

Intervention Type OTHER

Perceived Stress Scale (PSS)

The PSS is 14-item self-report tool commonly used to provide a global measure of perceived stress in daily life.

Intervention Type OTHER

Toronto Alexithymia Scale (TAS)

The TSA is a 20-item scale that evaluates the three components of alexithymia: difficulty to identify feelings and distinguish between feelings and bodily sensations of emotional arousal difficulty, describing feelings to others, and a cognitive style that is literal, utilitarian, and externally oriented.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients \> 18 years old (both males and females).
* Patients diagnosed with colorectal cancer.
* Patients scheduled for elective open or laparoscopic surgery for curative intent.

Exclusion Criteria

* Patients unable to give the written informed consent.
* Patients \< 18 years old.
* Patients undergoing surgery in emergency setting.
* Patients with pre-operative evidence of metastatic cancer or colorectal cancer recurrence.
* Pregnant or breastfeeding patients.
* Any condition that, in the opinion of the investigator, can interfere with the study protocol (e.g. neuropsychiatric disorders or dementia).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Istituto Clinico Humanitas

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Antonino Spinelli, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Istituto Clinico Humanitas

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

IRCCS Istituto Clinico Humanitas, Division of Colon and Rectal Surgery

Milan, MI, Italy

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Italy

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Annalisa Maroli, PhD

Role: CONTACT

Phone: +.39 02 8224 7776

Email: [email protected]

Francesca De Lucia, MD

Role: CONTACT

Phone: +39 028224 7776

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Annalisa Maroli, PhD

Role: primary

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

1945

Identifier Type: -

Identifier Source: org_study_id