Tibial Nerve Stimulation and Postoperative Ileus

NCT ID: NCT02815956

Last Updated: 2017-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-04

Study Completion Date

2017-06-09

Brief Summary

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Postoperative ileus (POI) causes patient's discomfort and leads to an increase of cost of management after colorectal surgery because of an increase of the morbidity rate or of the rate of early rehospitalization after discharge.

Enhanced recovery programs allowed a reduction of its rate but 20 to 30% of patients will experiment POI.

A new approach during preoperative era, using mastication or preoperative physical activity, has been proposed to improve postoperative course. This leads to a vagal activation (action especially on upper GI).

Sacral stimulation using percutaneous tibial nerve stimulation (PTNS) has an effect on lower GI.

The aim of this study was to assess the efficacy and the feasibility of PTNS during perioperative course, to prevent POI with respect with placebo.

Detailed Description

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Conditions

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Postoperative Ileus

Keywords

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percutaneous tibial nerve stimulation randomized controlled study

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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percutaneous tibial nerve stimulation (ST)

Stimulation the day before surgery (x1), 30 minutes Stimulation the day of surgery, before surgery (at least 2 hours before surgery) and after surgery.

Stimulation every day (x3) after surgery until gastrointestinal functions recovery.

The protocol of stimulation is the same, that the one performed for fecal incontinence.

Group Type EXPERIMENTAL

percutaneous tibial nerve stimulation

Intervention Type DEVICE

placebo (P)

Stimulation the day before surgery (x1), 30 minutes Stimulation the day of surgery, before surgery (at least 2 hours before surgery) and after surgery.

Stimulation every day (x3) after surgery until gastrointestinal functions recovery.

The device delivers ineffective impulses.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DEVICE

Interventions

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percutaneous tibial nerve stimulation

Intervention Type DEVICE

Placebo

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* patients \> 18 years
* elective colectomy or proctectomy
* agreement for the research

Exclusion Criteria

* chronic inflammatory bowel disease
* irritable bowel disease documented
* history of surgery on oesophagus or stomach
* acetylcholine dysfunction
* enterostoma
* patient holder of pace-maker
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Angers

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Aurélien Venara, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital Center of Angers

Locations

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University Hospital Center

Angers, , France

Site Status

Countries

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France

Other Identifiers

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2016-A00438-43

Identifier Type: -

Identifier Source: org_study_id