Empirical Antibiotic and Outcome in Community-onset Bacteremia

NCT ID: NCT03765749

Last Updated: 2022-04-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

108 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-11-22

Study Completion Date

2021-12-31

Brief Summary

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Empirical antibiotic and outcome in Community-onset Bacteremia Caused by third generation cephalosporin resistant Enterobacteriaceae

Detailed Description

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Prospective cohort study is conducted for monitoring outcomes and risk factors among community-onset bacteremia caused by third generation cephalosporin resistant enterobacteriaceae.

Primary endpoint is mortality rate among those who received initially inappropriate antimicrobial which switch to appropriate antimicrobial later when culture and antimicrobial susceptibility test reported among community-onset bacteremia caused by third generation cephalosporin resistant enterobacteriaceae.

Conditions

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Bacteremia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Community onset 3rd generation cephalosporin resistant entero

Patient with Community onset third generation cephalosporin resistant enterobacteriaceae bacteremia who received inappropriate Antibiotic

No interventions assigned to this group

Nosocomial onset 3rd generation cephalosporin resistant ente

Patient with Nosocomial onset third generation cephalosporin resistant enterobacteriaceae bacteremia who received appropriate Antibiotic

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patient with Community-onset Bacteremia Caused by third generation cephalosporin resistant Enterobacteriaceae. Age \> 18 years

Exclusion Criteria

* Pregnancy
* Polymicrobial infection
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Phramongkutklao College of Medicine and Hospital

OTHER

Sponsor Role lead

Responsible Party

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Vasin Vasikasin

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Worapong Nasomsong

Bangkok, , Thailand

Site Status

Countries

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Thailand

References

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Nasomsong W, Changpradub D, Vasikasin V. Impact of Inappropriate Empirical Antibiotic on Outcomes in Community-acquired Third Generation Cephalosporin Resistant Enterobacterales Bacteremia. Infect Chemother. 2022 Dec;54(4):722-732. doi: 10.3947/ic.2022.0096.

Reference Type DERIVED
PMID: 36596682 (View on PubMed)

Other Identifiers

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PMK-032

Identifier Type: -

Identifier Source: org_study_id

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