Nurse Promotion of IV to PO Antimicrobial Conversion

NCT ID: NCT03761043

Last Updated: 2019-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

853 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-08

Study Completion Date

2019-04-07

Brief Summary

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This is a prospective, quasi-experimental, historically controlled study to evaluate if a behavioural change intervention informed by the COM-B model of behaviour change can improve nurses' self-perceived capability, opportunity, and motivation to engage in the assessment of patients who may be appropriate for IV to PO antimicrobial conversion. This study also seeks to determine if this translates into an increase in IV to PO antimicrobial conversion rates in the acute care setting.

Detailed Description

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Current antimicrobial stewardship guidelines recommend appropriate and timely IV to PO antimicrobial conversion in hospitalized patients. Published rates of IV to PO antimicrobial conversion are consistently below 50% in eligible inpatients. Studies have suggested that nurses may be well positioned to provide a positive influence on prescriber behavior related to antimicrobial IV to PO conversion, however, no published research has evaluated the impact of nurses on antimicrobial IV to PO conversion rates. Published research has described the barriers and enablers to nurse participation in promoting antimicrobial IV to PO conversion using the COM-B model of behaviour change. This quasi-experimental study will evaluate whether determinants of nurse behaviour and their actual behaviour can be changed to increase antimicrobial IV to PO conversion rates in hospitalized patients.

Conditions

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Behavior Change Bacterial Infections

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Pre-Intervention Arm

The nurses will have not been exposed to the behavior change intervention.

Group Type NO_INTERVENTION

No interventions assigned to this group

Post-Intervention Arm

The nurses will have been exposed to the behavior change intervention.

Group Type EXPERIMENTAL

Professional Behavior Change Intervention

Intervention Type BEHAVIORAL

IV to PO antimicrobial conversion guidelines for nurses, nurse in-services and internet education sessions, IV to PO antimicrobial conversion health record reminder, endorsement from antimicrobial stewardship program, prescribers, and nurse educators.

Interventions

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Professional Behavior Change Intervention

IV to PO antimicrobial conversion guidelines for nurses, nurse in-services and internet education sessions, IV to PO antimicrobial conversion health record reminder, endorsement from antimicrobial stewardship program, prescribers, and nurse educators.

Intervention Type BEHAVIORAL

Other Intervention Names

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Printed educational materials Educational meetings Educational outreach visits Local opinion leaders Reminders

Eligibility Criteria

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Inclusion Criteria

* Nineteen years of age or older
* Employed as a RN or LPN at KGH in any capacity (full-time, part-time or casual employee)
* Practicing on a medicine/thoracic surgery ward (4A) or medicine/oncology/respiratory ward (4B)

Exclusion Criteria

* RNs or LPNs on orientation shifts/training
* RNs or LPNs not engaged in patient care
* Student nurses/nurses in training
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kelowna General Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Sean Gorman

Pharmacy Coordinator, Clinical Quality & Research

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Victoria Cox, PharmD

Role: PRINCIPAL_INVESTIGATOR

Interior Health Authority

Locations

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Kelowna General Hospital

Kelowna, British Columbia, Canada

Site Status

Countries

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Canada

References

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Fisher CC, Cox VC, Gorman SK, Lesko N, Holdsworth K, Delaney N, McKenna C. A theory-informed assessment of the barriers and facilitators to nurse-driven antimicrobial stewardship. Am J Infect Control. 2018 Dec;46(12):1365-1369. doi: 10.1016/j.ajic.2018.05.020. Epub 2018 Aug 1.

Reference Type BACKGROUND
PMID: 30077436 (View on PubMed)

Other Identifiers

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IH1803202

Identifier Type: -

Identifier Source: org_study_id

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