Singapore Cardiac Longitudinal Outcomes Database

NCT ID: NCT03760705

Last Updated: 2020-03-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

7205000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-07-05

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The research project aims to perform data extraction, integration and analysis across multiple clinical, administrative, financial and pharmacy databases in the participating institutions. The key data components will include clinical cardiovascular specific data, procedural data, financial and administrative data (e.g. cost of medications and supplies, length of stay, diagnosis codes etc.), short-to-long term clinical outcomes (including hospital re-admissions, cardiovascular events, death), and quality-of-care indices (e.g. compliance to guideline-recommended therapy and medications). The research project will involve all patients proven and/or suspected with coronary artery disease (CAD), congestive heart failure (CHF) and atrial fibrillation (AF) admitted to National Heart Centre Singapore (NHCS) and NUH.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The research project is initiated by NHCS and its participating institutions include Ministry of Health (MOH), as well as National University Hospital (Singapore) Pte Ltd (NUH), Changi General Hospital (CGH), Khoo Teck Puat Hospital (KTPH), Singapore General Hospital (SGH), Tan Tock Seng Hospital (TTSH), Ng Teng Fong General Hospital (NTFGH) , SingHealth Polyclinics, National Healthcare Group Polyclinics (NHGP), Sengkang Hospital (SKH), National University Polyclinics (NUP), and Alexandra Hospital (AH).

The research project will leverage on the Health Data Grid (HDG) pilot project, now known as Business Research Analytics Insights Network (BRAIN). BRAIN will be a virtual repository that will enable access to anonymised and merged data from disparate databases at multiple institutions. The structures of BRAIN will preserve patients' privacy and confidentiality, ensure IT security and allow access only by authorised persons. The BRAIN pilot project will be co-funded by MOH and the Infocommunication Media Development Authority of Singapore (IMDA). To avoid doubt, after the BRAIN pilot project, a separate approval from the appropriate stakeholders will have to be sought for further funding of the operating costs of the BRAIN, regardless of whether the value of the BRAIN has been demonstrated during the BRAIN pilot project. There is no direct cost involved in the research project.

For the research project, MOH will contribute administrative data from the Registry of Births and Deaths, Casemix \& Subvention, the Mediclaim, and Omnibus databases, and the other participating institutions will contribute the data from the National Electronic Health Records (NEHR), Electronic Health Intelligence System (eHIntS) and Enterprise Data Warehouse (EDW) to BRAIN. Only anonymised data from BRAIN will be utilised for the research project.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coronary Artery Disease Congestive Heart Failure Atrial Fibrillation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Coronary Artery Disease

1. Clinical data collected by Singapore Cardiac Data Bank (SCDB)
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by the Ministry of Health

Data Collection

Intervention Type OTHER

1. Collection of data as detailed below:

1. Clinical data collected by SCDB
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by MOH
2. Data will be extracted and anonymized on a secure healthcare analytics platform
3. Collaboration with the MOH for collection of administrative and financial data
4. Analysis on how healthcare behavior is affected by education, socioeconomic level and other social or cultural factors.
5. Statistical Analysis by the bio statistical team. This team will be responsible for collecting and merging the collected data and will also ensure the quality of the data.

Heart Failure

1. Clinical data collected by Singapore Cardiac Data Bank (SCDB)
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by the Ministry of Health

Data Collection

Intervention Type OTHER

1. Collection of data as detailed below:

1. Clinical data collected by SCDB
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by MOH
2. Data will be extracted and anonymized on a secure healthcare analytics platform
3. Collaboration with the MOH for collection of administrative and financial data
4. Analysis on how healthcare behavior is affected by education, socioeconomic level and other social or cultural factors.
5. Statistical Analysis by the bio statistical team. This team will be responsible for collecting and merging the collected data and will also ensure the quality of the data.

Atrial Fibrillation

1. Clinical data collected by Singapore Cardiac Data Bank (SCDB)
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by the Ministry of Health

Data Collection

Intervention Type OTHER

1. Collection of data as detailed below:

1. Clinical data collected by SCDB
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by MOH
2. Data will be extracted and anonymized on a secure healthcare analytics platform
3. Collaboration with the MOH for collection of administrative and financial data
4. Analysis on how healthcare behavior is affected by education, socioeconomic level and other social or cultural factors.
5. Statistical Analysis by the bio statistical team. This team will be responsible for collecting and merging the collected data and will also ensure the quality of the data.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Data Collection

1. Collection of data as detailed below:

1. Clinical data collected by SCDB
2. Clinical, administrative, pharmacy, financial data collected by each participating hospital
3. Administrative data collected by MOH
2. Data will be extracted and anonymized on a secure healthcare analytics platform
3. Collaboration with the MOH for collection of administrative and financial data
4. Analysis on how healthcare behavior is affected by education, socioeconomic level and other social or cultural factors.
5. Statistical Analysis by the bio statistical team. This team will be responsible for collecting and merging the collected data and will also ensure the quality of the data.

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* all patients who present to a healthcare institution with either CAD or suspected CAD (including chest pain); CHF or suspected CHF; AF or suspected AF

Exclusion Criteria

* non-Singaporeans
Minimum Eligible Age

21 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ministry of Health, Singapore

OTHER_GOV

Sponsor Role collaborator

Changi General Hospital

OTHER

Sponsor Role collaborator

National University Hospital, Singapore

OTHER

Sponsor Role collaborator

Singapore General Hospital

OTHER

Sponsor Role collaborator

Tan Tock Seng Hospital

OTHER

Sponsor Role collaborator

Khoo Teck Puat Hospital

OTHER

Sponsor Role collaborator

SingHealth Polyclinics

OTHER

Sponsor Role collaborator

National Healthcare Group, Singapore

OTHER_GOV

Sponsor Role collaborator

Ng Teng Fong General Hospital

OTHER

Sponsor Role collaborator

Sengkang General Hospital

OTHER

Sponsor Role collaborator

National University Polyclinics

UNKNOWN

Sponsor Role collaborator

Alexandra Hospital

OTHER

Sponsor Role collaborator

National Heart Centre Singapore

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Khung Keong Yeo

Role: PRINCIPAL_INVESTIGATOR

National Heart Centre Singapore

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

National University Hospital (Singapore) Pte Ltd

Singapore, , Singapore

Site Status

National Healthcare Group Polyclinics

Singapore, , Singapore

Site Status

SingHealth Polyclinics

Singapore, , Singapore

Site Status

Alexandra Hospital

Singapore, , Singapore

Site Status

Singapore General Hospital

Singapore, , Singapore

Site Status

National Heart Centre Singapore

Singapore, , Singapore

Site Status

Ministry of Health

Singapore, , Singapore

Site Status

Tan Tock Seng Hospital Pte Ltd

Singapore, , Singapore

Site Status

Changi General Hospital

Singapore, , Singapore

Site Status

National University Polyclinics

Singapore, , Singapore

Site Status

Ng Teng Fong General Hospital

Singapore, , Singapore

Site Status

Khoo Teck Puat Hospital

Singapore, , Singapore

Site Status

Sengkang Hospital

Singapore, , Singapore

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Singapore

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CIRB/2013-391/C

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Health Data Warehouse on Aortic Insufficiency
NCT06420895 ACTIVE_NOT_RECRUITING