Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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ACTIVE_NOT_RECRUITING
1000 participants
OBSERVATIONAL
2011-01-01
2033-12-31
Brief Summary
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The aim is to enable the utilisation of this data for research purposes.
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Detailed Description
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Data will be collected exclusively by the person responsible for implementing the data processing and his/her authorised staff. For all patients, data will be collected retrospectively, based on medical records (electronic or paper), and information available on the various care software linked to the patient's file. There will not be changes in the the patient's care.
At the GHICL Valvulopathy Centre, in accordance with European recommendations, patients with aortic insufficiency are monitored as follows, depending on the severity of the pathology:
* Minimal aortic insufficiency: follow-up every 3-5 years (approximately) including clinical examination and transthoracic echocardiogram (TTE)
* Moderate/medium aortic insufficiency: follow-up every 1-2 years with clinical examination, laboratory tests and TTE.
* Significant aortic insufficiency: follow-up every 6-12 months including a clinical examination, a biological assessment and a c+/- TTE coupled with an exercise test.
* Cardiac Magnetic Resonance Imaging (MRI) indicated as a second-line procedure after TTE in cases of moderate/medium aortic insufficiency with arguments or doubts about an underestimation of the severity of the aortic insufficiency on TTE, aortic insufficiency of undetermined quantification on TTE, or significant aortic insufficiency on TTE to confirm the severity using a multiparametric approach.
* TEE (transesophageal echocardiogram) is indicated as 2nd line after TTE in cases of significant aortic insufficiency as part of the preoperative work-up or moderate/undetermined aortic insufficiency on TTE.
The choice between cardiac MRI or TEE, or both, as second-line treatment after TEE, is left to the clinician in current practice, in accordance with the recommendations.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Group of patients with aortic insufficiency
Patients already assessed at GHICL's Valvulopathy Centre from 2011 to October 2023 will be identified retrospectively, by queries based on keywords and/or diagnostic codes in echocardiography interpretation software (Viewpoint/EchoPAC, ISCV). GHICL's Medical Information Department will also be involved.
Clinical follow-up
Clinical follow-up of patients
Transthoracic Echocardiogram (TTE)
Transthoracic Echocardiogram
Magnetic resonance imaging (MRI)
Magnetic resonance imaging
Transesophageal echocardiogram (TEE)
Transesophageal echocardiogram
Interventions
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Clinical follow-up
Clinical follow-up of patients
Transthoracic Echocardiogram (TTE)
Transthoracic Echocardiogram
Magnetic resonance imaging (MRI)
Magnetic resonance imaging
Transesophageal echocardiogram (TEE)
Transesophageal echocardiogram
Eligibility Criteria
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Inclusion Criteria
* Cared for at GHICL Since 1st January 2011
* With chronic aortic insufficiency of any grade.
Exclusion Criteria
* Patients with acute heart failure
* Patients with an intracardiac shunt or other complex congenital heart disease or obstructive hypertrophic cardiomyopathy
* Patients with aortic prosthesis
* Patients with active endocarditis or sequelae \< 6 months old
* Patients under legal protection
* Patient who refused to take part in the study
* Patients with other than minimal left heart valve disease (with the exception of secondary mitral insufficiency)
18 Years
ALL
No
Sponsors
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Lille Catholic University
OTHER
Responsible Party
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Principal Investigators
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Other Identifiers
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EDS-2023-02
Identifier Type: -
Identifier Source: org_study_id
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