Effect of Camel Milk on Insulin and Incretin Response

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-02-01

Study Completion Date

2020-12-30

Brief Summary

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To examine the differential effect of camel and cow milk on the physiological response, to a liquid mixed-meal challenge, in people with normal glucose tolerance

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Detailed Description

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Camel milk is used as a traditional remedy throughout the Middle East and Indian Subcontinent for conditions such as type 2 diabetes and dyslipidemia. It is currently unclear how such an effect could be mediated in vivo and studies are limited. We performed this study as a pilot experiment to assess the effects of camel milk on Insulin, Glucose, GLP-1, C-peptide and Lipid profile.

Conditions

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Insulin Sensitivity Glucose Tolerance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Participants Investigators

Double-blind

Study Groups

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Healthy individuals (camel milk)

Group Type EXPERIMENTAL

Camel milk

Intervention Type DIETARY_SUPPLEMENT

Camel Milk administered 10 minutes before a mixed meal of carbohydrate and protein; 2-week washout between interventions

Healthy individuals (cow milk)

Group Type EXPERIMENTAL

Cow milk

Intervention Type DIETARY_SUPPLEMENT

Cow milk administered 10 minutes before a mixed meal of carbohydrate and protein;2-week washout between interventions

Interventions

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Camel milk

Camel Milk administered 10 minutes before a mixed meal of carbohydrate and protein; 2-week washout between interventions

Intervention Type DIETARY_SUPPLEMENT

Cow milk

Cow milk administered 10 minutes before a mixed meal of carbohydrate and protein;2-week washout between interventions

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Normal glucose tolerance
* BMI \< 30 kg/m2

Exclusion Criteria

* Type 1 diabetes mellitus
* Type 2 diabetes mellitus
* Impaired fasting glucose or impaired glucose tolerance
* Lactose intolerance
* Weight loss / gain ≥ 5 kg in the preceding two months
* Use of estrogenic drugs or corticosteroids
* Known hypertriglyceridemia requiring treatment
* History of heart attack, angina or cardiovascular disorder
* History of malignant tumor
* Pregnant or lactating women
* Hemoglobin \< 12 for any reason
* Recent surgery or major hemorrhage
* History of bariatric or metabolic surgery

Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes