Diagnosis of Renal Osteodystrophy in Patients With Reduced Renal Function
NCT ID: NCT03716128
Last Updated: 2025-03-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
40 participants
OBSERVATIONAL
2018-09-26
2027-10-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
1. To describe the bone morphology in patients with reduced renal function and high or low parathyroid hormone (PTH) respectively.
2. To investigate if the non-invasive method 18-Fluoride Positron Emission Tomography (18F-PET) can describe the bone turnover and reflect the bone histomorphologic changes
3. To investigate if non-oxidized PTH reflects bone turnover
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Renal Osteodystrophy: A Fresh Approach
NCT00859612
Clinical Observation on Bone Metabolism Induced by Chronic Renal Insufficiency
NCT02147782
Bone Structure in Patients With Adult Onset Growth Hormone Deficiency Assessed Using High Resolution Peripheral Quantitative Computed Tomography
NCT02218710
Immunophenotyping in Patients With Osteoporosis
NCT05132348
Study on the Predictive Value of the Natural Calcium Isotope Ratio in Urine and Serum for the Diagnosis of Osteoporosis
NCT02967978
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
A bone biopsy and a 18F-PET scan are performed and it is investigated if the 18F-PET can discriminate high turnover from low turnover bone disease
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
OTHER
CROSS_SECTIONAL
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Low turnover bone disease
PTH\<150 pg/ml
18F-PET
Bone biopsy and 18F-PET
High turnover bone disease
PTH\>300 pg/ml
18F-PET
Bone biopsy and 18F-PET
Normal renal function
Patients under examination for prostate cancer
18F-PET
Bone biopsy and 18F-PET
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
18F-PET
Bone biopsy and 18F-PET
Other Intervention Names
Discover alternative or legacy names that may be used to describe the listed interventions across different sources.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* estimated Glomerular Filtration Rate (eGFR) ≤ 20 ml/min/1,73m2
* PTH \< 150 pg/ml or PTH \> 300 pg/ml
-≥ 18 years
* eGFR \>= 60 ml/min
* under examination for c prostata
* Prostatic Specific Antigen (PSA) total \<40 µg/l
Exclusion:
* Former kidney disease
* ionized calcium or PTH outside normal range
* Known metabolic bone disease
* treatment with anticoagulants
* Disturbed thrombosis and hemostasis
Exclusion Criteria
* Allergy towards tetracyclin
* Pregnancy
Control Group:
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University of Copenhagen
OTHER
Universiteit Antwerpen
OTHER
Ditte Hansen
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Ditte Hansen
Associate professor
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Herlev Hospital
Herlev, , Denmark
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
H-17040409
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.