The Comparison of PYY, Ghrelin, GLP1, Glucose Level, Level of Satiety, and Ad Libitum Intake in Obese and Non-Obese Patients After Breakfast With Balanced Macronutrient Composition
NCT ID: NCT03701503
Last Updated: 2018-10-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2010-10-31
2011-07-31
Brief Summary
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The research methodology was used a clinical trial with 18 obese women and 22 non obese women participants. Subjects were given a balance breakfast (protein 12,4%, carbohydrate 68,2%, fat 22,6%). Gut hormones (PYY, Ghrelin, GLP -1) level , Glucose level and satiety level were measured at 0, 15, 60, 120, and 180 minutes after breakfast. Ad libitum meal was given four hours after breakfast and measured after.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Obese
Women age 20-40, with BMI ≥ 25-35 kg/m2 Given a balanced breakfast (Protein 12,4%, carbohydrate 68,2%, fat 22,6%) with calories according to their energy requirement,which is calculated by adding basal metabolic rate (BMR) with additional energy from physical activity.
Participants' blood was taken before intervention, and 15, 60, 120, and 180 minutes after intervention, then examined in laboratory to measure every outcome. After 4 hours, participants were given ad libitum meal. After the participants done eating, the calorie in meal taken by participants was measured.
Diet with balance composition to know the effect of a meal to gut hormones in obese and non obese women
Non Obese
Women age 20-40, with BMI 18,5-23 kg/m2 Given a balanced breakfast (Protein 12,4%, carbohydrate 68,2%, fat 22,6%) with calories according to their energy requirement,which is calculated by adding basal metabolic rate (BMR) with additional energy from physical activity.
Participants' blood was taken before intervention, and 15, 60, 120, and 180 minutes after intervention, then examined in laboratory to measure every outcome. After 4 hours, participants were given ad libitum meal. After the participants done eating, the calorie in meal taken by participants was measured.
Diet with balance composition to know the effect of a meal to gut hormones in obese and non obese women
Interventions
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Diet with balance composition to know the effect of a meal to gut hormones in obese and non obese women
Eligibility Criteria
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Inclusion Criteria
* BMI 18,5 - 23 (for NON- obese am)
* with stable body weight within the last 6 months (body weight change less than 4 kg)
* normal blood glucose level.
Exclusion Criteria
* patients in weight loss program
* patients consuming lipid-absorption inhibitor or appetite-suppressing drugs
* patients that have had gastrointestinal tract resection.
20 Years
40 Years
FEMALE
Yes
Sponsors
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SEAMEO Regional Centre for Food and Nutrition
OTHER
Dr Cipto Mangunkusumo General Hospital
OTHER
Indonesia University
OTHER
Responsible Party
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Fiastuti Witjaksono
Principal Investigator
Locations
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Departement of Nutrition, Faculty of Medicine Universitas Indonesia
Jakarta, Jakarta Pusat, Indonesia
Countries
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Other Identifiers
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GuthormoneOB-NonOB
Identifier Type: -
Identifier Source: org_study_id
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