2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
NCT ID: NCT03700788
Last Updated: 2023-03-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE3
40 participants
INTERVENTIONAL
2023-05-30
2025-08-31
Brief Summary
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Detailed Description
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The primary objective of the proposed study is to determine if there is a difference in 7-day (+/- 2) post-procedure apical periodontitis following randomization to either 2% chlorohexidine vs. calcium hydroxide paste among patients presenting with symptoms of apical periodontitis. Additionally, the investigators will assess the number of adverse events that occur in each treatment group to determine if there appears to be a difference across groups, descriptively.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Clorhexidine
2% Chlorhexidine
Chlorhexidine
2% Chorhexidine (intracranial; remains in canal until removal at next visit)
Calcium Hydroxide
Calcium Hydroxide
Calcium Hydroxide
Calcium Hydroxide (intracranial; remains in canal until removal at next visit)
Interventions
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Chlorhexidine
2% Chorhexidine (intracranial; remains in canal until removal at next visit)
Calcium Hydroxide
Calcium Hydroxide (intracranial; remains in canal until removal at next visit)
Eligibility Criteria
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Inclusion Criteria
* symptomatic apical periodontitis (positive to the bite test)
* restorable tooth
* requires root canal therapy
* able to undergo informed consent process
* must be English or Spanish speaker
Exclusion Criteria
* non-restorable tooth
* no pain medication or antibiotic taken in the past 3 days
18 Years
80 Years
ALL
Yes
Sponsors
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University of Southern California
OTHER
Responsible Party
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Ramon Roges
Associate Professor, Director
Principal Investigators
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Rafael Roges, D.D.S.
Role: STUDY_DIRECTOR
Director, Advanced Endodontics
Locations
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Herman Ostrow USC School of Dentistry
Los Angeles, California, United States
Countries
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Central Contacts
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Other Identifiers
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HS-17-00292
Identifier Type: -
Identifier Source: org_study_id
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