Diagnostic Accuracy of Human Transcriptional Activator(MYB) Expression by ELISA Technique Versus Immmunohistochemistry in Detecting Salivary Gland Carcinomas

NCT ID: NCT03687294

Last Updated: 2020-07-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

70 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-12

Study Completion Date

2021-12-31

Brief Summary

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in this resarch we will use ELISA Technique to estimate Human Transcriptional Activator(MYB) Expression .compare it by Immmunohistochemistry analysis of MYB Expression in the malignant and benign salivary gland tumor

Detailed Description

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Conditions

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Malignant Neoplasm of Salivary Gland Benign Neoplasm of Salivary Gland

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Group I

patients suffering from malignant salivary gland tumors.

enzyme linked immunosorbent assay (ELISA)

Intervention Type DEVICE

ELISA measure MYB in tissue biopsy in benign and malignant salivary gland tumors

Group II

patients suffering from benign salivary gland tumors.

enzyme linked immunosorbent assay (ELISA)

Intervention Type DEVICE

ELISA measure MYB in tissue biopsy in benign and malignant salivary gland tumors

Interventions

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enzyme linked immunosorbent assay (ELISA)

ELISA measure MYB in tissue biopsy in benign and malignant salivary gland tumors

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients with clinically evident salivary gland tumors; malignant tumors will be recruited in group I
* Benign tumors will be recruited in group II.

Exclusion Criteria

* Subjects taking any drugs inducing any changes that could affect the salivary glands.
* Pregnant females.
* Subjects having any allergies, infectious or autoimmune diseases.
* Subjects having any metabolic disorders that can be manifested with salivary gland swelling as diabetes mellitus.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Yousra Refaey

pricipal investegator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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National Cancer Institute

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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yousra refaey

Role: CONTACT

01014458092

Fat'heya Zahran

Role: CONTACT

01060775113

Facility Contacts

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Role: primary

0223689711

Other Identifiers

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yousrarefaey11

Identifier Type: -

Identifier Source: org_study_id

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