Supplementing Intracytoplasmic Sperm Injection Handling Medium With Cytochalasin D ( ICSI-CD)

NCT ID: NCT03677492

Last Updated: 2019-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-09-25

Study Completion Date

2019-04-30

Brief Summary

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Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Cytochalasin D serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Cytochalasin D during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes.

Detailed Description

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Conditions

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Infertility

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Handling Medium Supplemented with Cytochalasin D

Group Type EXPERIMENTAL

Medium Supplemented with Cytochalasin D

Intervention Type OTHER

A medium with in-house supplementation of Cytochalasin D to decrease oocyte degeneration after ICSI and improve the survival rate

Handling Medium as it is.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Medium Supplemented with Cytochalasin D

A medium with in-house supplementation of Cytochalasin D to decrease oocyte degeneration after ICSI and improve the survival rate

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ICSI indicated participants

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

42 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ibn Sina Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Muhammad Fawzy

IVF Lab Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Banon Assiut

Asyut, , Egypt

Site Status

IbnSina IVF Center, IbnSina Hospital

Sohag, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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IbnSinaIVF-ICSI-CD

Identifier Type: -

Identifier Source: org_study_id

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