Motor Evoked Potentials With Modified Facilitation Technique

NCT ID: NCT03646929

Last Updated: 2021-05-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

81 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-12-20

Study Completion Date

2019-01-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Investigating the change in Test- Retest- reliability in healthy individuals when applying a modified easy to use facilitation technique compared to standard facilitation technique and analyzing sensitivity and specificity in patients with multiple sclerosis regarding detection of pathologic results

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Multiple Sclerosis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

healthy individuals and patients with multiple sclerosis

MEP in healthy individuals and patients with multiple sclerosis are measured using standard facilitation technique

Group Type OTHER

MEP using standard facilitation technique

Intervention Type DIAGNOSTIC_TEST

measuring of MEP using standard facilitation technique according to the Guidelines of International Federation of Clinical Neurophysiology

patients with multiple sclerosis

MEP in patients with multiple sclerosis are measured using modified facilitation technique

Group Type OTHER

MEP using standard facilitation technique

Intervention Type DIAGNOSTIC_TEST

measuring of MEP using standard facilitation technique according to the Guidelines of International Federation of Clinical Neurophysiology

MEP using modified facilitation technique

Intervention Type DIAGNOSTIC_TEST

measuring of MEP using modified facilitation technique (application of additional 8-12x magnetic stimuli for arms and legs)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

MEP using standard facilitation technique

measuring of MEP using standard facilitation technique according to the Guidelines of International Federation of Clinical Neurophysiology

Intervention Type DIAGNOSTIC_TEST

MEP using modified facilitation technique

measuring of MEP using modified facilitation technique (application of additional 8-12x magnetic stimuli for arms and legs)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Ability to understand the purpose and risks of the study, provide signed and dated informed consent
* Between 18 and 65 year of age
* No neurologic or psychiatric comorbidity requiring continous treatment
* No previous damage of central nervous System


* Ability to understand the purpose and risks of the study, provide signed and dated informed consent
* Between 18 and 65 year of age
* patients with inflammatory diseases of the central nervous system (CNS) or multiple sclerosis appointed for routine MEP diagnostic at the Department of Clinical Neurophysiology, University Hospital Basel

Exclusion Criteria

* Contraindication for measuring of motoric evoked potentials (MEP): metal implants (pacemaker, stents); known epilepsy oder previous epileptic fit
* Known disease of the peripheral nervous system (polyneuropathy)
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University Hospital, Basel, Switzerland

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Martin Hardmeier, PD Dr. med

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Basel, Switzerland

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Dep. of Neurology and Clinical Neurophysiology , Hospital of the University of Basel

Basel, , Switzerland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Switzerland

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2017-01893; me18Hardmeier

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.