The Effect of Mental Fatigue on Lower Limb Functional Performance Tests and Brain Activity in a Healthy Population

NCT ID: NCT03643406

Last Updated: 2019-07-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 13 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-10-19
• Study Completion Date: 2019-07-17

Brief Summary

Objective of the study

The main objectives of this project are:

1. To assess the influence of mental fatigue on a return-to-play test battery in healthy population

2. To assess the influence of mental fatigue on brain functioning during a balance and reaction time task in healthy population In a later stage, these experiments could be carried out in a clinical context (e.g. in an ankle sprain population).

The researchers will use a randomized, placebo controlled, counter-balanced, cross-over design.

Thirteen healthy subjects will visit the lab 3 times. On the first visit (familiarisation trial), the investigators will collect the participants' characteristics. The participants will also be familiarized to the procedures and materials of the experiment during this first visit. The second and third visit contain the experimental setup and will proceed as follows: first, the participants will fill in a mental fatigue scale (M-VAS) and motivation scale. Next, the subjects will carry out a functional test battery (hop test, vertical jump test, Y-balance test, and a balance reaction-time test). Session rate of perceived exertion (RPE) is measured to indicate how fatigued the participants feel because of the test battery; also, M-VAS is collected once more. Then, a short cognitive task (Flanker task) is followed by either a long intensive cognitive task (90 minutes Stroop task) or control task (90 minutes documentary). Afterwards, participants have to carry out the Flanker task, fill in M-VAS (2x), perform the same test battery, fill in session RPE and one final fatigue scale (Nasa TLX). Heart frequency and EEG will be measured continuously during the trials.

Conditions

Mental Fatigue; Return to Sport; EEG; Brain Activity; Functional Performance

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: SINGLE

Study Groups

Mental Fatigue Condition

Group Type: EXPERIMENTAL

Mental Fatigue

Intervention Type: OTHER

modified stroop task

Control Condition

Group Type: PLACEBO_COMPARATOR

Control

Intervention Type: OTHER

documentary

Interventions

Mental Fatigue

modified stroop task

Intervention Type: OTHER

Control

documentary

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Healthy (No neurological/cardiorespiratory/psychological disorders)
• Male and female
• No medication
• Non-smoker
• Between 18 and 35 years old

Exclusion Criteria

• Back and/or lower extremity injuries during the past 6 months
• Bone/joint abnormalities
• Dizziness, history of loss of consciousness, any inner ear disorders
• Nervous system disorders or dysfunctions
• Uncorrected eye disorders/dysfunctions
• Illness
• Use of medication or any kind of drugs
• Use of alcohol, caffeine and heavy efforts 24 hours before each trial
• Not eating the same meal the night before and the morning of each trial

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 35 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Vrije Universiteit Brussel

OTHER

Sponsor Role: lead

Responsible Party

Romain Meeusen

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Vrije Universiteit Brussel

Brussels, , Belgium

Countries

Belgium

Other Identifiers

143201836625

Identifier Type: -

Identifier Source: org_study_id