Role of Low Inferior Mesenteric Artery Ligation During Laparoscopic Surgery for Rectosigmoid Cancer

NCT ID: NCT03557528

Last Updated: 2018-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-01

Study Completion Date

2017-04-30

Brief Summary

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During sigmoid or rectal cancer surgery, dissection of lymphnodes at the origin of inferior mesenteric artery is mandatory. Nevertheless, ligation of the origin of IMA should compromise blood supply to left colon and affect anastomosis. The aim of this retrospective evaluation is to compare high and low IMA ligation with preservation of LCA, with or without skeletonization of the origin of IMA in laparoscopic colorectal resection.

Detailed Description

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Conditions

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Rectosigmoid Adenocarcinoma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group 1

High Ligation of Inferior mesenteric artery

Laparoscopic colorectal resection

Intervention Type PROCEDURE

Gruop 1: laparoscopic rectosigmoid resection with standard ligation of mesenteric artery at its origin Group 2: Laparoscopic rectosigmoid resection with low ligation of inferior mesenteric artery and its skeletonization with en bloc removal of all lymph nodes

Group 2

Low ligation of inferior mesenteric artery with skeletonization at its origin

Laparoscopic colorectal resection

Intervention Type PROCEDURE

Gruop 1: laparoscopic rectosigmoid resection with standard ligation of mesenteric artery at its origin Group 2: Laparoscopic rectosigmoid resection with low ligation of inferior mesenteric artery and its skeletonization with en bloc removal of all lymph nodes

Interventions

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Laparoscopic colorectal resection

Gruop 1: laparoscopic rectosigmoid resection with standard ligation of mesenteric artery at its origin Group 2: Laparoscopic rectosigmoid resection with low ligation of inferior mesenteric artery and its skeletonization with en bloc removal of all lymph nodes

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* stage I-III carcinoma

Exclusion Criteria

* stage IV
* Urgent resection
* conversion to open surgery
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Roma La Sapienza

OTHER

Sponsor Role lead

Responsible Party

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DANIELE CROCETTI

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Policlinico Umberto I

Roma, , Italy

Site Status

Countries

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Italy

Other Identifiers

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14ur2018

Identifier Type: -

Identifier Source: org_study_id

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