Fluid Immersion Simulation (FIS) System Versus Air Fluidized Bed (AFB) System for Pressure Ulcers

NCT ID: NCT03522714

Last Updated: 2023-05-03

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-08-08

Study Completion Date

2020-12-31

Brief Summary

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The primary objective is to compare the efficacy of the FIS on closure rate to the AFB after 2 weeks of operative debridement and closure.

Detailed Description

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Secondary Objectives:

1. Compare the complication rate in each treatment group during the acute postoperative period (2 weeks).
2. Comparisons of the inflammatory and bacterial microbiomes of pressure ulcers following surgical therapy.
3. Comparisons of baseline patient characteristics and their relationship to both early and late pressure ulcer recurrence, and complication rates.
4. Assessment of outcomes and complications associated with flap technique and surgeon guided descriptions of the operative closure.
5. Compare the absolute costs associated with the FIS System against AFB system.
6. Compare the acceptance of each system by subjects and nursing staff, including the parameter of patient comfort at 7 and 14 days postoperative.
7. Assessing the incidence of complications and additional treatments needed following the two week study period.

Conditions

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Pressure Ulcer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

1:1 allocation ratio
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Fluid Immersion Simulation System (FIS)

Pressure ulcer patients are assigned to Fluid Immersion Simulation System (Dolphin) after operative debridement and closure.

Group Type ACTIVE_COMPARATOR

Fluid Immersion Simulation System

Intervention Type DEVICE

Dolphin Fluid Immersion Simulation® System Mattress will be used

Air Fluidized Bed System (AFB)

Pressure ulcer patients are assigned to Air Fluidized Bed (Clinitron) after operative debridement and closure

Group Type ACTIVE_COMPARATOR

Air Fluidized Bed System

Intervention Type DEVICE

Air Fluidized Bed (Clinitron) will be used.

Interventions

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Fluid Immersion Simulation System

Dolphin Fluid Immersion Simulation® System Mattress will be used

Intervention Type DEVICE

Air Fluidized Bed System

Air Fluidized Bed (Clinitron) will be used.

Intervention Type DEVICE

Other Intervention Names

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FIS, Dolphin AFB, Clinitron

Eligibility Criteria

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Inclusion Criteria

1. will be admitted as an inpatient
2. is ≥ 18 years of age and ≤ 85 years of age at time of consent
3. is able to provide his/her own informed consent
4. is deemed by the investigators to be reasonably compliant
5. has a pressure ulcer meeting criteria for stage III or IV
6. has not participated in a clinical trial within the past 30 days
7. has a 30-day wound history available if the wound has been previously treated

Exclusion Criteria

1. has a life expectancy of \< 12 months
2. is not healthy enough to undergo surgery for any reason
3. has a history of radiation therapy
4. is, in the opinion of the investigator, noncompliant
5. has a history of \> 3 closures of pressure ulcers in the same site
6. has a history of a bleeding disorder
7. has severe fecal incontinence
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Northwestern University

OTHER

Sponsor Role lead

Responsible Party

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Robert Galiano

Associate Professor of Surgery (Plastic Surgery) and Dermatology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Robert D Galiano, MD

Role: PRINCIPAL_INVESTIGATOR

Northwestern Medicine

Locations

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Northwestern Memorial Hospital Plastic Surgery

Chicago, Illinois, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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STU00200584

Identifier Type: -

Identifier Source: org_study_id

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