Cortical Priming to Optimize Gait Rehabilitation Post Stroke
NCT ID: NCT03492229
Last Updated: 2022-08-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
81 participants
INTERVENTIONAL
2014-01-01
2020-08-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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tDCS+AMT
TDCS in combination with movement training before treadmill training
tDCS
1 mA of tDCS
AMT
Ankle motor training
Treadmill training
High intensity treadmill training
tDCS
tDCS only before treadmill training
tDCS
1 mA of tDCS
Treadmill training
High intensity treadmill training
AMT
Movement training only before treadmill training
AMT
Ankle motor training
Treadmill training
High intensity treadmill training
Control
No priming before treadmill training
Treadmill training
High intensity treadmill training
Interventions
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tDCS
1 mA of tDCS
AMT
Ankle motor training
Treadmill training
High intensity treadmill training
Eligibility Criteria
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Inclusion Criteria
* First ever monohemispheric stroke \> 6 months since onset
* Residual hemiparetic gait deficits
* Able to walk without an ankle orthotic for 5 minutes at self-paced speed. Handheld assistive device is acceptable.
Exclusion Criteria
* Contracture-limiting range of motion of lower limb
* Uncontrolled anti-spasticity medications during the study period
* Cardiorespiratory or metabolic diseases (e.g. cardiac arrhythmia, uncontrolled hypertension or diabetes, chronic emphysema)
* Unhealed decubiti, persistent infection
* Significant cognitive or communication impairment (MMSE \<21), which could impede the understanding of the purpose of procedures of the study or prevent the patient from performing the tracking task.
* Lesions pertaining to the brainstem and cerebellum
40 Years
80 Years
ALL
No
Sponsors
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Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
University of Illinois at Chicago
OTHER
Responsible Party
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Sangeetha Madhavan
Associate Professor
Principal Investigators
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Sangeetha Madhavan
Role: PRINCIPAL_INVESTIGATOR
UIC
Locations
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The University of Illinois at Chicago
Chicago, Illinois, United States
Countries
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References
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Madhavan S, Cleland BT, Sivaramakrishnan A, Freels S, Lim H, Testai FD, Corcos DM. Cortical priming strategies for gait training after stroke: a controlled, stratified trial. J Neuroeng Rehabil. 2020 Aug 17;17(1):111. doi: 10.1186/s12984-020-00744-9.
Other Identifiers
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2011-0676
Identifier Type: -
Identifier Source: org_study_id
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