Auditory Temporal Processes in Aging

NCT ID: NCT03468660

Last Updated: 2022-03-14

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 82 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-01-18
• Study Completion Date: 2020-06-30

Brief Summary

Older people experience great difficulty understanding speech, especially accented English, and this problem is expected to increase with the influx of immigrants who provide services to the elderly population. The research examines the underlying factors that contribute to older listeners' difficulty understanding accented speech, including those associated with age-related hearing loss, changes in processing in auditory pathways in the brain, and general cognitive decline. The investigation also evaluates the efficacy of training strategies to improve understanding of accented English by older people. Outcomes of this research are expected to improve communication between senior citizens and those with whom they interact daily, and thereby improve quality of life for the older segment of the Nation's population.

Detailed Description

This research program in speech perception and auditory psychophysics examines the hypothesis that many of the predominant difficulties in speech understanding of elderly listeners are related to underlying problems in auditory temporal processing. One form of degraded speech that is particularly difficult for elderly listeners to perceive is accented English. Alterations of speech stress and timing with accent may be viewed as a form of degradation in temporal aspects of speech prosody, and this type of temporal distortion is the focus of investigation in the next project period. Moreover, psychoacoustic results demonstrate that large age-related difficulties in temporal processing exist for the perception of auditory tempo and rhythmic characteristics of sequential stimulus patterns featuring a stressed tone. Listener processing difficulty could be attributed to peripheral and/or central processing mechanisms, as well as various cognitive factors, including the degree of familiarity with prosodic features of different native languages. The project examines the relative contribution of peripheral hearing impairment, type of stimulus temporal complexity and cognitive demand, and the linguistic background experience of listeners on the processing of temporal prosody cues in speech and non-speech stimulus patterns. The project associated with this clinical trial examines the efficacy of auditory training paradigms with stimuli that feature temporal contrasts for improving perception of accented English and non-speech sequences by older people. The research described in this application seeks to address one goal outlined by the National Institute on Aging: to develop effective interventions to maintain health and function and prevent or reduce the burden of age-related diseases, disorders, and disabilities. The approach in this research program involves (a) an assessment of the problems encountered in daily activities by the elderly population, (b) an analysis of specific task demands in relation to individual capabilities, and (c) basic research on sensory and perceptual changes with age and on the ameliorating effects of emerging technologies (including rehabilitation). This three-dimensional approach is expected to further progress toward improving communication and health-related quality of life for senior citizens.

Conditions

Auditory Perceptual Disorders; Aging Problems

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: HEALTH_SERVICES_RESEARCH
• Blinding Strategy: NONE

Study Groups

Experimental group

Auditory training with feedback

Group Type: EXPERIMENTAL

Auditory training with feedback

Intervention Type: BEHAVIORAL

Experimental group receives phoneme-level and sentence-level training with feedback

Passive control group

Pre-post testing only; no training

Group Type: NO_INTERVENTION

No interventions assigned to this group

Active Control group

Listening task with no feeback

Group Type: ACTIVE_COMPARATOR

Listening paradigm with no feedback

Intervention Type: BEHAVIORAL

Active controls listen to acoustic stimuli with no feedback

Interventions

Auditory training with feedback

Experimental group receives phoneme-level and sentence-level training with feedback

Intervention Type: BEHAVIORAL

Listening paradigm with no feedback

Active controls listen to acoustic stimuli with no feedback

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Age and hearing sensitivity:
• Younger listeners (18-40 years) with normal hearing;
• Older listeners (65-80 years) with normal hearing;
• Older listeners (65-80 years) with bilateral, mild-to-moderate sensorineural hearing loss.
• High School Diploma,
• native speaker of English (based on self-report)
• normal middle-ear function (based on tympanometry)
• normal cognitive function (based on score on Montreal Cognitive Assessment)
• good-to-excellent word recognition scores (based on Northwestern University Test # 6 word recognition scores presented in quiet at suprathreshold levels).

Exclusion Criteria

• non-native speaker of English,
• motor and/or speech disorders that prevent participant from providing a time-locked response,
• presence of middle ear disease or conductive hearing loss,
• presence of severe or profound hearing loss,
• presence of poor word recognition scores,
• cognitive impairment.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Maryland, College Park

OTHER

Sponsor Role: lead

Responsible Party

Sandra Gordon Salant

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Sandra Gordon-Salant, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Maryland

Locations

University of Maryland

College Park, Maryland, United States

Countries

United States

References

Gordon-Salant S, Yeni-Komshian GH, Bieber RE, Jara Ureta DA, Freund MS, Fitzgibbons PJ. Effects of Listener Age and Native Language Experience on Recognition of Accented and Unaccented English Words. J Speech Lang Hear Res. 2019 Apr 26;62(4S):1131-1143. doi: 10.1044/2018_JSLHR-H-ASCC7-18-0122.

Reference Type: BACKGROUND

PMID: 31026190 (View on PubMed)

Bieber RE, Yeni-Komshian GH, Freund MS, Fitzgibbons PJ, Gordon-Salant S. Effects of listener age and native language on perception of accented and unaccented sentences. J Acoust Soc Am. 2018 Dec;144(6):3191. doi: 10.1121/1.5081711.

Reference Type: BACKGROUND

PMID: 30599683 (View on PubMed)

Bieber RE, Gordon-Salant S. Adaptation to novel foreign-accented speech and retention of benefit following training: Influence of aging and hearing loss. J Acoust Soc Am. 2017 Apr;141(4):2800. doi: 10.1121/1.4980063.

Reference Type: RESULT

PMID: 28464671 (View on PubMed)

Fitzgibbons PJ, Gordon-Salant S. Age effects in discrimination of intervals within accented tone sequences differing in accent type and sequence presentation rate. J Acoust Soc Am. 2016 Nov;140(5):3819. doi: 10.1121/1.4967512.

Reference Type: RESULT

PMID: 27908085 (View on PubMed)

Gordon-Salant S, Yeni-Komshian GH, Pickett EJ, Fitzgibbons PJ. Perception of contrastive bi-syllabic lexical stress in unaccented and accented words by younger and older listeners. J Acoust Soc Am. 2016 Mar;139(3):1132-48. doi: 10.1121/1.4943557.

Reference Type: RESULT

PMID: 27036250 (View on PubMed)

Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ, Cohen JI. Effects of age and hearing loss on recognition of unaccented and accented multisyllabic words. J Acoust Soc Am. 2015 Feb;137(2):884-97. doi: 10.1121/1.4906270.

Reference Type: RESULT

PMID: 25698021 (View on PubMed)

Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ, Cohen JI, Waldroup C. Recognition of accented and unaccented speech in different maskers by younger and older listeners. J Acoust Soc Am. 2013 Jul;134(1):618-27. doi: 10.1121/1.4807817.

Reference Type: RESULT

PMID: 23862836 (View on PubMed)

Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ. Recognition of accented English in quiet and noise by younger and older listeners. J Acoust Soc Am. 2010 Nov;128(5):3152-60. doi: 10.1121/1.3495940.

Reference Type: RESULT

PMID: 21110610 (View on PubMed)

Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ, Schurman J. Short-term adaptation to accented English by younger and older adults. J Acoust Soc Am. 2010 Oct;128(4):EL200-4. doi: 10.1121/1.3486199.

Reference Type: RESULT

PMID: 20968326 (View on PubMed)

Gordon-Salant S, Yeni-Komshian GH, Fitzgibbons PJ. Recognition of accented English in quiet by younger normal-hearing listeners and older listeners with normal-hearing and hearing loss. J Acoust Soc Am. 2010 Jul;128(1):444-55. doi: 10.1121/1.3397409.

Reference Type: RESULT

PMID: 20649238 (View on PubMed)

Fitzgibbons PJ, Gordon-Salant S. Age-related differences in discrimination of temporal intervals in accented tone sequences. Hear Res. 2010 Jun 1;264(1-2):41-7. doi: 10.1016/j.heares.2009.11.008. Epub 2009 Dec 3.

Reference Type: RESULT

PMID: 19931608 (View on PubMed)

Other Identifiers

UMDCP

Identifier Type: -

Identifier Source: org_study_id