Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery
NCT ID: NCT03455751
Last Updated: 2019-03-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
10 participants
INTERVENTIONAL
2018-04-17
2019-01-09
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
SINGLE
Study Groups
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Control
The control arm will receive no intervention and will follow standard of care for post-operative pain management.
No interventions assigned to this group
PGx-guided
The PGx-guided arm will received altered post-operative pain management based on the results of pharmacogenomic testing.
PGx-guided post-operative pain management
Post-operative pain management as indicated by pharmacogenomic testing results.
Interventions
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PGx-guided post-operative pain management
Post-operative pain management as indicated by pharmacogenomic testing results.
Eligibility Criteria
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Inclusion Criteria
* Age 18-80
* Scheduled for open colorectal resection at Cleveland Clinic main campus (with preoperative appointment scheduled at least five days before date of surgery)
Exclusion Criteria
* Patient with substance-use disorder (including alcohol)
* Patient diagnosed with major depression
* Patient currently taking opioids
* Previous long-term opioid use (\> 3 months)
* Previous opioid use with a dose of \>100 milligram morphine equivalent (MME)
* Patient has pain-related disorder (e.g. fibromyalgia, sympathetic dystrophy, etc.)
* Documented allergy to pain medication
18 Years
80 Years
ALL
No
Sponsors
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The Cleveland Clinic
OTHER
Responsible Party
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David Liska
Associate Staff, Colorectal Surgery
Principal Investigators
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David Liska, MD
Role: PRINCIPAL_INVESTIGATOR
The Cleveland Clinic
Locations
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Cleveland Clinic
Cleveland, Ohio, United States
Countries
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Other Identifiers
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17-1540
Identifier Type: -
Identifier Source: org_study_id
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