Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer Patients

NCT ID: NCT04762914

Last Updated: 2021-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

52 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-09-01

Study Completion Date

2019-12-31

Brief Summary

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Quality Improvement Project to evaluate how prehabilitation can be incorporated into our colorectal cancer pathway and assess its clinical benefits.

Detailed Description

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The aim was to evaluate how prehabilitation (PH) can be incorporated into our colorectal cancer pathway and assess its clinical benefits.

Patients underwent PH (exercise, nutrition and psychological support) before resection of colorectal carcinoma in a DGH over fourteen months. Patients were matched by operation, age, sex and ASA to non-prehabilitation (NPH) patients using a prospectively maintained database. Length of stay (LoS) and complication rate and 90-day readmission rates were compared using Wilcoxon and McNemar's methods.

Prehabilitation significantly improved peak VO2 and AT. This corresponds to a reduction in predicted 30-day mortality. Despite a higher Charlson index LoS was unchanged suggesting prehabilitation may permit safe resection in comorbid patients.

Conditions

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Colon Cancer

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Prehabilitation (PH)

Patients who underwent prehabilitation prior to colorectal cancer resection

Prehabilitation

Intervention Type OTHER

Prehabilitation is a multimodal and multidisciplinary person-centred perioperative approach involving supervised exercise training, nutritional education, management of polypharmacy and psychological advice.

Non-Prehabilitation (NPH)

Patients who did not undergo prehabilitation prior to colorectal cancer resection

No interventions assigned to this group

Interventions

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Prehabilitation

Prehabilitation is a multimodal and multidisciplinary person-centred perioperative approach involving supervised exercise training, nutritional education, management of polypharmacy and psychological advice.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults over the age of 18 who had prehabilitation for colorectal cancer

Exclusion Criteria

* Children
* Patients who had prehabilitation but not for colorectal cancer
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Medway Primary Care Trust

OTHER_GOV

Sponsor Role lead

Responsible Party

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Richard Dickson-Lowe

Consultant Surgeon

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Richard A Dickson-Lowe

Role: PRINCIPAL_INVESTIGATOR

Medway PCT

Locations

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Medway Hospitals NHS Trust

Gillingham, Kent, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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2021.038N

Identifier Type: -

Identifier Source: org_study_id

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