High-flow Nasal Oxygen in Palliative Care: Pilot Study

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-02-13

Study Completion Date

2022-01-25

Brief Summary

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In palliative care, the relief of the dyspnea is necessary. Medications for the reduction of dyspnea have side effects. High-flow nasal cannula oxygen therapy (HFNC) is a new way to deliver oxygen. Investigators hypothesize that HNFC is an acceptable technic for the patient with dyspnea in palliative care.

A pilot study with 30 patients will be conducted. Acceptability of HNFC will be studied by the time of use by patients of the HNFC during one week. The effectiveness of HNFC in relieving dyspnea will be studied using Borg scale.

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Detailed Description

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Pilot study for acceptability of high flow nasal cannula oxygen therapy in palliative care Population: 30 patients in palliative care (for lung cancer, terminal respiratory failure) who suffer from dyspnea and have oxygen therapy. Patients with curative care are excluded and patients who require non invasive ventilation.

An oral consent is asked.

Primary objective: acceptability of HNFC in patients with dyspnea in palliative care during one week

Secondary objectives:

* Tolerance of HNFC at short term (1h and 24h) and long term (7 days) after initiation of HNFC
* Efficiency of HNFC at short term

Primary outcome: duration of use of the HNFC during 7 days

Secondary outcome:

* Tolerance: noise of the system of HNFC, side effects of high flow (nasal dryness..)
* Efficiency: evaluation of dyspnea by Borg scale and measure of respiratory rate and saturation of oxygen one hour after initiation of HNFC

Conditions

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Dyspnea

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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High-flow nasal oxygen

Group Type EXPERIMENTAL

high-flow nasal cannula oxygen therapy (HNFC)

Intervention Type DEVICE

Set up of high-flow nasal oxygen for patient with dyspnea for a respiratory disease without possibility of curative care. Patients who require a treatment by oxygen are included.

After 7 days of treatment, acceptability is evaluated by the duration of use of HNFC.

Interventions

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high-flow nasal cannula oxygen therapy (HNFC)

Set up of high-flow nasal oxygen for patient with dyspnea for a respiratory disease without possibility of curative care. Patients who require a treatment by oxygen are included.

After 7 days of treatment, acceptability is evaluated by the duration of use of HNFC.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient followed for respiratory failure with palliative care and :
* More than 18 years old
* Dyspnea related to a respiratory disease
* Hypoxemia requiring the introduction of more than 4 liters of oxygen for a sp02 \> 90%
* Patient affiliated to a social security system