Analgesic Value of Adductor Canal vs Femoral Block After Total Knee Arthroplasty

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-03-27

Study Completion Date

2016-10-19

Brief Summary

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An observational study of the effect of femoral nerve block in addition to an adductor canal block for pain following total knee arthroplasty.

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Detailed Description

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Subjects undergoing total knee arthroplasty will receive a preoperative adductor canal block with continuous catheter. Following a standardized general anesthetic for the procedure, subjects will be asked to rate their pain using the NRS-11 pain scale in the recovery room. Once the pain is reported at a 5/10 or above, a femoral nerve block will be performed using either 2% chloroprocaine or saline placebo (randomized). Pain scores are then evaluated over the next 30 minutes by a blinded investigator to determine if the femoral block adds any additional analgesic benefit over an adductor canal block.

Conditions

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Osteo Arthritis Knee

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

randomized, blinded observational study

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Group allocation by sealed envelope; unblinded investigator prepared syringes of study drug (chloroprocaine vs. saline), which look identical to blinded investigator and assessor.

Study Groups

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chloroprocaine

15 ml of 2% chloroprocaine via a femoral nerve block technique

Group Type ACTIVE_COMPARATOR

Active comparator: chloroprocaine

Intervention Type PROCEDURE

15 ml of 2% chloroprocaine was placed under ultrasound guidance adjacent to the femoral nerve in the operative limb.

saline

15 ml of 0.9% saline via a femoral nerve block technique

Group Type SHAM_COMPARATOR

Sham comparator: saline

Intervention Type PROCEDURE

15 ml of normal saline was placed under ultrasound guidance adjacent to the femoral nerve in the operative limb.

Interventions

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Active comparator: chloroprocaine

15 ml of 2% chloroprocaine was placed under ultrasound guidance adjacent to the femoral nerve in the operative limb.

Intervention Type PROCEDURE

Sham comparator: saline

15 ml of normal saline was placed under ultrasound guidance adjacent to the femoral nerve in the operative limb.

Intervention Type PROCEDURE

Other Intervention Names

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femoral nerve block with chloroprocaine femoral nerve block with normal saline

Eligibility Criteria

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Inclusion Criteria

* Patients scheduled for elective total knee arthroplasty
* ASA Physical Status I-III
* BMI 18-40 kg/m2

Exclusion Criteria

* Inability to cooperate with protocol
* Inability to understand or speak English
* Allergy to any local anesthetic
* Chronic opioid consumption/abuse (30 or more morphine mg equivalents/day)
* Contraindication to adductor canal or femoral nerve block

Minimum Eligible Age

56 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No