Study of the Efficacy of 4 Treatments for Fecal Incontinence in Community-dwelling Women

NCT ID: NCT03394794

Last Updated: 2018-01-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-02-01

Study Completion Date

2017-03-01

Brief Summary

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This is a RCT aimed to assessing efficacy of kegel exercises,biofeedback, electrostimulation and transcutaneous neuromodulation on women with fecal incontinence, measuring its impact on anorectal physiology, cortical plasticity, clmical severity and the quality of life.

Detailed Description

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Fecal incontinence is a prevalent condition with a major impact on quality of life. Currently four treatments are being used in clinical practice: Kegel exercises (K), biofeedback (BF), electrostimulation (ES) and transcutaneous neuromodulation (NM). Results in the literature are discordant and lack methodological rigour making scientific evidence weak.

The aim of this study is to assess the efficacy of these four treatments on community-dwelling women and their impact on anorectal physiology, on clinical severity and on QoL.

This is a randomized control trial. Patient physiology was studied with anorectal manometry and endoanal ultrasonography; clinical severity was assessed with Cleveland and St. Mark's scales, and QoL with the Faecal Incontinence Quality of Life (FIQL) and the EuroQol's EQ5D questionnaires. Urinary incontinence (UI) was also evaluated by means of International Consultation on Incontinence (ICIQ) score. Patients were randomized and assigned to K (control), BF+K, ES+K or NM+K, given active treatment for a 3-month period, and then evaluated again with identical tests and parameters to identify changes.

Conditions

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Fecal Incontinence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Kegel exercises

Pelvic floor exercises designed in the 1950s' by Arnold Kegel.

Group Type ACTIVE_COMPARATOR

Pelvic floor rehabilitation

Intervention Type DEVICE

The aim is to compare how each treatment improves symptoms and quality of life and which physiologic mechanisms affects. The basal treatment which other therapies are compared to is Kegel.

biofeedback

Biofeeback therapy to improve neuromuscular coordination and strengthen sphincter contractility.

Group Type EXPERIMENTAL

Pelvic floor rehabilitation

Intervention Type DEVICE

The aim is to compare how each treatment improves symptoms and quality of life and which physiologic mechanisms affects. The basal treatment which other therapies are compared to is Kegel.

electrostimulation

Administration of electric current with a specific device (stimulator) and through a vaginal prove, in order to improve pelvic floor contractility.

Group Type EXPERIMENTAL

Pelvic floor rehabilitation

Intervention Type DEVICE

The aim is to compare how each treatment improves symptoms and quality of life and which physiologic mechanisms affects. The basal treatment which other therapies are compared to is Kegel.

transcutaneous neuromodulation

Stimulation of tibial nerve with a specific electric current through a stimulator and surface electrodes

Group Type EXPERIMENTAL

Pelvic floor rehabilitation

Intervention Type DEVICE

The aim is to compare how each treatment improves symptoms and quality of life and which physiologic mechanisms affects. The basal treatment which other therapies are compared to is Kegel.

Interventions

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Pelvic floor rehabilitation

The aim is to compare how each treatment improves symptoms and quality of life and which physiologic mechanisms affects. The basal treatment which other therapies are compared to is Kegel.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age higher than 18
* To be woman
* Have had incontinence episiodes at least from 6 month since the beginning of the study
* Have had incontinence episodes during the last month prior the beginning of the study
* The patient is able to understand the nature and impliations of the study and, therefore, to decide her participation.

* Have very mild condition (Wexner \<4)
* To be unable to perform / understand the treatments properly
* Being pregnant
* To have used treatmets for fecal incontinence within the last six months prior to the start of the study
* If, at reserarcher's criteria, the patient has not the proper conditions to perform and finish the treatments.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hospital de Mataró

OTHER

Sponsor Role lead

Responsible Party

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Lluís Mundet

GI motility clinician / researcher

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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IF02-11/2012

Identifier Type: -

Identifier Source: org_study_id

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