Atropine Weight and Risk of Postoperative Confusion in the Elderly

NCT ID: NCT03390751

Last Updated: 2020-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-12-14

Study Completion Date

2022-01-31

Brief Summary

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The identification of a high atropine load of treatment received during hospitalization as a predictor of postoperative confusion could have various benefits:

* Pharmacoepidemiological: identify factors associated with postoperative confusion
* Clinics: by favoring treatments with a low atropine load during anesthesia, the management of patients hospitalized in orthopedics. Similarly, stopping or re-evaluating treatments with a high atropine weight for scheduled surgery is an easy step to take.
* Socio-economic: by reducing the costs related to the occurrence of a confusional syndrome (over-treatment, prolonged hospital stay, loss of autonomy, institutionalization of patients...).

In total, the present study would improve the daily management of hospitalized patients and the practices of clinicians, by offering a decision-making aid.

Detailed Description

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Conditions

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Aging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Aged patients

Data collection of patients admitted to the orthopedic department of the University Hospital of Toulouse for surgical management of a fracture of the upper end of the femur in emergency or for the installation of a hip or knee prosthesis.

Data collection

Intervention Type OTHER

The collection of data will be done by interrogation of the patient and his family / entourage and rereading of medical records

Interventions

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Data collection

The collection of data will be done by interrogation of the patient and his family / entourage and rereading of medical records

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Admitted to the orthopedic department for surgical management of a fracture of the upper end of the femur in emergency or for the installation of a hip or knee prosthesis
* Patient able to understand and respond to the protocol
* No opposition to the collection of data of the patient or his / her designee

Exclusion Criteria

* Pre-existing confusion to surgery, detected by the CAM scale
* Serious or moderate head trauma less than three months old
* Removing / installing prosthesis.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Toulouse

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vincent Minville

Role: PRINCIPAL_INVESTIGATOR

University Hospital, Toulouse

Locations

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Pierre-Paul-Riquet University Hospital

Toulouse, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Vincent Minville, MD PhD

Role: CONTACT

33-5 61 32 27 91

Marie PIEL-JULIAN

Role: CONTACT

Facility Contacts

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Vincent Minville, MD

Role: primary

Other Identifiers

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2017-A01847-46

Identifier Type: REGISTRY

Identifier Source: secondary_id

RC31/17/0202

Identifier Type: -

Identifier Source: org_study_id

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