Prevention of Postoperative Delirium After Acute Surgery
NCT ID: NCT04857125
Last Updated: 2021-04-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
476 participants
INTERVENTIONAL
2021-04-12
2022-03-31
Brief Summary
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The hypothesis is that the frequency of postoperative delirium will be reduced after implementation of the preventive interventions.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
SEQUENTIAL
PREVENTION
SINGLE
Study Groups
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Multicomponent intervention
Pre-, intra- and postoperative interventions applied using the Fast-IM method.
Patient interventions
The multicomponent intervention consists of several elements regarding avoidance of specific pre-medications and optimising the patients condition before surgery (reducing fasting and fluid-fasting time).
Per-operative focus on using bispectral index (BIS) guided anaesthesia, Total intravenous anaesthesia (TIVA) as first choice, pain-and PONV (postoperative nausea and vomiting) prophylaxis and treatment.
Postoperative focus on: Reducing indwelling catheters, Fluid (p.o. or IV), Nutrition, Mobilisation, Sleep, Non-pharmacological interventions (Shielding, involving of relatives, orientation, optimizing of senses)
Staff education
Staff will be educated for at least 1-2 hours. Anaesthesiologist and nurse anaesthetists will receive a brush up on the use of bispectral index (BIS) and the intervention elements that are implemented and monitored. Staff in the PACU, as well as staff in the surgery wards, will be educated in postoperative delirium, learning to identify symptoms of delirium and how to use the screening tool CAM.
Standard care
Patients are receiving standard care.
No interventions assigned to this group
Interventions
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Patient interventions
The multicomponent intervention consists of several elements regarding avoidance of specific pre-medications and optimising the patients condition before surgery (reducing fasting and fluid-fasting time).
Per-operative focus on using bispectral index (BIS) guided anaesthesia, Total intravenous anaesthesia (TIVA) as first choice, pain-and PONV (postoperative nausea and vomiting) prophylaxis and treatment.
Postoperative focus on: Reducing indwelling catheters, Fluid (p.o. or IV), Nutrition, Mobilisation, Sleep, Non-pharmacological interventions (Shielding, involving of relatives, orientation, optimizing of senses)
Staff education
Staff will be educated for at least 1-2 hours. Anaesthesiologist and nurse anaesthetists will receive a brush up on the use of bispectral index (BIS) and the intervention elements that are implemented and monitored. Staff in the PACU, as well as staff in the surgery wards, will be educated in postoperative delirium, learning to identify symptoms of delirium and how to use the screening tool CAM.
Eligibility Criteria
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Inclusion Criteria
* Patients scheduled for acute abdominal or orthopaedic surgery in general anaesthesia with an expected duration of 30 minutes or more.
* Patients who are scheduled for surgery within 72 hours of hospital admission.
* Patients who are expected to stay in hospital for 24 hours or more.
Exclusion Criteria
* Patients who have already been included in the study
* Patients unable to speak and read Danish.
* Inability to provide consent.
40 Years
ALL
No
Sponsors
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Bispebjerg Hospital
OTHER
Responsible Party
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Sine Eriksen
Principal Investigator
Principal Investigators
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Christian Meyhoff, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Copenhagen
Locations
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Bispebjerg and Frederiksberg Hospital
Copenhagen, , Denmark
Countries
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Central Contacts
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Facility Contacts
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Role: primary
Other Identifiers
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H-20067775
Identifier Type: -
Identifier Source: org_study_id
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