Prevalence of Delirium in Patients Undergoing Cardiac Surgery

NCT ID: NCT00242151

Last Updated: 2006-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Brief Summary

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The objective of this study is to determine prevalence of postoperative delirium and confusion in patients undergoing cardiac surgery. This proposal is a pilot study designed to evaluate effect of cardiac surgery on prevalence of delirium and confusion.

The primary aim is to evaluate prevalence of delirium and confusion in patients undergoing cardiac surgery and to determine risk factors for this condition.

A secondary aim is to evaluate organic brain injury by early postoperative diffusion weighted magnetic resonance imaging (DW-MRI) in patients who develop delirium and confusion.

The hypothesis to be tested is that patients with postoperative delirium and confusion have high incidence of organic brain injury as detected by DW-MRI.

Detailed Description

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Conditions

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Heart Disease

Keywords

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Delirium, Confusion, Cardiac Surgery, Organic Brain Injury, Diffusion Weighted Magnetic Resonance Imaging (DW-MRI)

Study Design

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Observational Model Type

DEFINED_POPULATION

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* All patients undergoing cardiac surgery in our institute in 2 year period
* Signed informed consent

Exclusion Criteria

* Past history of transient ischemic attacks, stroke, symptomatic carotid artery disease.
* Past history of psychiatric disorders
* History of alcohol and drug abuse
* History of severe kidney or liver disease (creatinine \>2.5mg/dL and bilirubin \> 2mg/dL)
* Known contraindications to MRI
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Health Network, Toronto

OTHER

Sponsor Role lead

Principal Investigators

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Rita Katznelson, MD

Role: PRINCIPAL_INVESTIGATOR

Toronto General Hospital, University Health Network

Locations

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Toronto General Hospital, University Health Network

Toronto, Ontario, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Jo A Carroll, RN

Role: CONTACT

Phone: 416-340-4800

Email: [email protected]

Facility Contacts

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Jo A Carroll, RN

Role: primary

Other Identifiers

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UHN REB 05-0223-AE

Identifier Type: -

Identifier Source: org_study_id