Comparing Effectiveness of Merocel and Packing With Tranexamic Acid in the Management of Anterior Epistaxis
NCT ID: NCT03360045
Last Updated: 2018-08-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
135 participants
INTERVENTIONAL
2018-05-01
2018-08-01
Brief Summary
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In this study, patients who presented with non-traumatic anterior epistaxis to emergency departments will be included in this study. Three different therapy option are created; first, nasal compression with tranexamic acid, second, simple nasal compression without any drugs. And third, packing with Merocel.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Tranexamic acid group
500mg tranexamic acid is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
Tranexamic Acid
500mg tranexamic acid is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
Placebo group
5ml normal saline is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
Normal saline
5 cc normal saline is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
Merocel Group
Merocel packing is applied.
Merocel
Merocel packing is applied.
Interventions
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Tranexamic Acid
500mg tranexamic acid is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
Normal saline
5 cc normal saline is sprayed in the nose by atomizer spray, and then is applied nasal compression by manually.
Merocel
Merocel packing is applied.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients who used anticoagulation therapy
* Patients who have hemodynamically instability
* Traumatic epistaxis
* Patients who have known bleeding disorder
18 Years
80 Years
ALL
No
Sponsors
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Kecioren Education and Training Hospital
OTHER
Responsible Party
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Şeref Kerem Çorbacıoğlu
Associated professor
Locations
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Keçiören Training and Research Hospital
Ankara, , Turkey (Türkiye)
Countries
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References
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Akkan S, Corbacioglu SK, Aytar H, Emektar E, Dagar S, Cevik Y. Evaluating Effectiveness of Nasal Compression With Tranexamic Acid Compared With Simple Nasal Compression and Merocel Packing: A Randomized Controlled Trial. Ann Emerg Med. 2019 Jul;74(1):72-78. doi: 10.1016/j.annemergmed.2019.03.030. Epub 2019 May 9.
Other Identifiers
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71146310-511.06-E.223856
Identifier Type: -
Identifier Source: org_study_id
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