Tranexamic Acid : Nebulization vs IV Route for Hemoptysis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

172 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-01

Study Completion Date

2025-10-31

Brief Summary

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This study compares the effect of tranexamic acid on hemoptysis when given through the conventional IV route and Through nebulization.

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Detailed Description

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The investigators are conducting a randomized controlled trial for the comparison of routes through which tranexamic acid can be given to control hemoptysis. The study participants will be divided into 2 groups randomly and 1 group will be assigned to use IV route while other will be assigned the nebulization route and the result variables include the time taken for complete control of hemoptysis and recurrence time. Another variable is the reduction in amout of blood in sputum after each intervention.

Conditions

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Hemoptysis NEBULIZATION Tranexamic Acid

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The intervention will be given to the participants via providing the tranexamic acide through both IV and nebulization routes.

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

There is no masking as the participnats will be explained the whole process and consent would be taken for using the either route for administration of tranexamic acid

Study Groups

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Group receiving tranexamic acid via IV route

Tranexamic acid has been used conventionally for hemoptysis via IV route

Group Type ACTIVE_COMPARATOR

Tranexamic Acid (TXA)

Intervention Type DRUG

In this study we are comparing the effect of tranexamic acid on hemoptysis when given through IV route and nebulization

The Group receiving tranexamic acid via nebulization

Tranexamic acid when given through nebulization can be more effective than IV route in controlling hemoptysis

Group Type EXPERIMENTAL

Tranexamic Acid (TXA)

Intervention Type DRUG

In this study we are comparing the effect of tranexamic acid on hemoptysis when given through IV route and nebulization

Interventions

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Tranexamic Acid (TXA)

In this study we are comparing the effect of tranexamic acid on hemoptysis when given through IV route and nebulization

Intervention Type DRUG

Other Intervention Names

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nebulization

Eligibility Criteria

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Inclusion Criteria

1. Patients with mild to moderate hemoptysis \< 600ml/ 24 hours of age 12 to 80 years and both genders.
2. Patients with hemoptysis due to infective pathology.
3. Patients with hemoptysis due to malignant pathology.