Risk Factors of Epistaxis Recurrence in Adults

NCT ID: NCT06657053

Last Updated: 2024-10-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

145 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-02

Study Completion Date

2025-04-01

Brief Summary

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We study all patients admitted to the Emergency Department in the Institution between 01/2022 and 07/2023. The information about the recurrence of nose bleeding was searched on their medical file and by calling the patient to confirm ou get the information. Thus, several potentiel risk factors were studied.

The relation between recurrence and those factors were studied at first individually and then all the significant ones were analyzed with a multivarious statistical test.

Detailed Description

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We study all patients admitted to the Emergency Department in the Institution between 01/2022 and 07/2023. The information about the recurrence of nose bleeding was searched on their medical file and by calling the patient to confirm ou get the information. Thus, several potentiel risk factors were studied : oral anticoagulants, sex, INR, anti-platelets drugs, diabetes, obesity, arterial hypertension, heart failure, hemoglobin at the admission, history of chronic rhinosinusitis, appointment with an ENT during the acute bleeding, sleep apnea, age, anatomic abnormality, recent surgery within 2 months, previous admission within 30 days in the emergency department, nasal trauma.

The relation between recurrence and those factors were studied at first individually and then all the significant ones were analyzed with a multivarious statistical test.

This study aim to provide a pronostic score of recurrence that can happen after the 3 fisrt weeks after the event. When a recurrence happens before 3 weeks, this was considered to be a non control of the bleeding episode.

This score will be then tested on our cohort to evaluate specificity and sensibility.

Conditions

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Epistaxis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patient with nose bleeding

Evaluation of recurrence epistaxis during the year after a first episode

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patient who is admitted at the emergency department between 01/2022 and 07/2023 for nose bleeding.
* Age over 18 yo

Exclusion Criteria

* Opposition to be included
* Patient who has not his willness to provide opposition to participate.opposition
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Grenoble Alpes

La Tronche, ISERE, France

Site Status

Countries

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France

Central Contacts

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Ashley BAGUANT, Doctor

Role: CONTACT

+33476764522

Facility Contacts

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Ashley BAGUANT, Doctor

Role: primary

+33476764522

References

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Addison A, Paul C, Kuo R, Lamyman A, Martinez-Devesa P, Hettige R. Recurrent epistaxis: predicting risk of 30-day readmission, derivation and validation of RHINO-ooze score. Rhinology. 2017 Jun 1;55(2):99-105. doi: 10.4193/Rhin16.259.

Reference Type BACKGROUND
PMID: 28434017 (View on PubMed)

Abrich V, Brozek A, Boyle TR, Chyou PH, Yale SH. Risk factors for recurrent spontaneous epistaxis. Mayo Clin Proc. 2014 Dec;89(12):1636-43. doi: 10.1016/j.mayocp.2014.09.009. Epub 2014 Nov 6.

Reference Type BACKGROUND
PMID: 25458126 (View on PubMed)

Chaaban MR, Zhang D, Resto V, Goodwin JS. Factors influencing recurrent emergency department visits for epistaxis in the elderly. Auris Nasus Larynx. 2018 Aug;45(4):760-764. doi: 10.1016/j.anl.2017.11.010. Epub 2017 Dec 6.

Reference Type BACKGROUND
PMID: 29208334 (View on PubMed)

Melia L, McGarry GW. Epistaxis: update on management. Curr Opin Otolaryngol Head Neck Surg. 2011 Feb;19(1):30-5. doi: 10.1097/MOO.0b013e328341e1e9.

Reference Type BACKGROUND
PMID: 21150620 (View on PubMed)

Pino Rivero V, Trinidad Ruiz G, Gonzalez Palomino A, Pardo Romero G, Pantoja Hernandez CG, Marcos Garcia M, Keituqwa Yanez T, Blasco Huelva A. [Considerations about ENT emergencies. Analysis of 30000 patients assisted in 10 years]. Acta Otorrinolaringol Esp. 2005 May;56(5):198-201. doi: 10.1016/s0001-6519(05)78600-3. Spanish.

Reference Type BACKGROUND
PMID: 15960122 (View on PubMed)

Pallin DJ, Chng YM, McKay MP, Emond JA, Pelletier AJ, Camargo CA Jr. Epidemiology of epistaxis in US emergency departments, 1992 to 2001. Ann Emerg Med. 2005 Jul;46(1):77-81. doi: 10.1016/j.annemergmed.2004.12.014.

Reference Type BACKGROUND
PMID: 15988431 (View on PubMed)

Tunkel DE, Anne S, Payne SC, Ishman SL, Rosenfeld RM, Abramson PJ, Alikhaani JD, Benoit MM, Bercovitz RS, Brown MD, Chernobilsky B, Feldstein DA, Hackell JM, Holbrook EH, Holdsworth SM, Lin KW, Lind MM, Poetker DM, Riley CA, Schneider JS, Seidman MD, Vadlamudi V, Valdez TA, Nnacheta LC, Monjur TM. Clinical Practice Guideline: Nosebleed (Epistaxis). Otolaryngol Head Neck Surg. 2020 Jan;162(1_suppl):S1-S38. doi: 10.1177/0194599819890327.

Reference Type BACKGROUND
PMID: 31910111 (View on PubMed)

Cohen O, Shoffel-Havakuk H, Warman M, Tzelnick S, Haimovich Y, Kohlberg GD, Halperin D, Lahav Y. Early and Late Recurrent Epistaxis Admissions: Patterns of Incidence and Risk Factors. Otolaryngol Head Neck Surg. 2017 Sep;157(3):424-431. doi: 10.1177/0194599817705619. Epub 2017 May 2.

Reference Type BACKGROUND
PMID: 28463569 (View on PubMed)

Other Identifiers

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EssaiClinique_FREA

Identifier Type: -

Identifier Source: org_study_id

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