Predictors for Recurrence of Atrial Fibrillation After Electrical Cardioversion

NCT ID: NCT03346863

Last Updated: 2021-05-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

270 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-11-01

Study Completion Date

2023-12-31

Brief Summary

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In patients with persistent atrial fibrillation (AF), electrical cardioversion is very effective in restoring sinus rhythm if modern, biphasic cardioverters are used. However, approximately 50 per cent of the successfully cardioverted patients experience a recurrence of AF within a few weeks. Therefore, valid predictors for AF recurrence would be of great clinical relevance, to avoid unnecessary procedures.

In the PRE-ELECTRIC study, we will investigate the predictive value of potential new biomarkers with respect to AF recurrence within 30 days after electrical cardioversion. We will investigate serum and plasma biomarkers, electrocardiological markers and echocardiographic variables in this respect. The study will be undertaken as a prospective cohort study at Bærum Hospital, Vestre Viken Hospital Trust, with national and international collaborators.

Detailed Description

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Conditions

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Atrial Fibrillation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients \> 18 years referred for electrical cardioversion for persistent atrial fibrillation
* Signed, informed consent

Exclusion Criteria

* Patients \< 18 years
* Patients with paroxysmal atrial fibrillation
* Patients unwilling to participate or without consent competence
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oslo University Hospital

OTHER

Sponsor Role collaborator

Lund University

OTHER

Sponsor Role collaborator

Vestre Viken Hospital Trust

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Bærum Hospital, Vestre Viken

Sandvika, Bærum, Norway

Site Status RECRUITING

Countries

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Norway

Central Contacts

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Arnljot Tveit, MD, PhD

Role: CONTACT

0047-97171773

Mona Olufsen, RN

Role: CONTACT

0047-90637441

Facility Contacts

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Arnljot Tveit, MD, PhD

Role: primary

0047-97171773

Elizabeth Lyster Andersen, MD

Role: backup

0047-90882242

Other Identifiers

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PRE-ELECTRIC 2017/1604

Identifier Type: -

Identifier Source: org_study_id

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