Predictive Value of Aortic Stiffness on Recurrence of Atrial Fibrillation After Disconnection of Pulmonary Veins (VARIABLE).
NCT ID: NCT03226639
Last Updated: 2017-07-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2016-11-30
2018-05-31
Brief Summary
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Risk factors for recidivism are poorly codified and need further research. Indeed the identification of factors of poor prognosis could lead to not propose this procedure to the patients who present them and at least to inform them of an increased risk of failure.
To date, aortic stiffness has not been studied in the context of assessing the risk factors for FA recurrence after ablation. On a physiopathological level, the aortic stiffness leads to increase left ventricle's post-load. Cardiac remodeling was observed with diastolic dysfunction and increased left atrial size. That may constitute a substrate for FA recurrence.
In the literature, aortic stiffness can be measured in several ways:
1. Measurement of systolo-diastolic variation of the inner diameter of the aorta by scanner or transesophageal Echography (ETO).
2. Measuring of the Pulse Wave Velocity.
3. Measurement of aortic calcifications.
The investigators propose to evaluate the impact of aortic stiffness on the recidivism of FA 6 months after ablation procedure performed in the Croix-Rousse cardiology's department.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Patient carrying a paroxysmal or persistent atrial fibrillation, benefiting from a first procedure of atrial fibrillation's ablation in the in the Croix-Rousse cardiology's department.
* Patient who signed the consent to participate in the study.
Exclusion Criteria
* Patient who're in atrial fibrillation during the ablation
* Atrial fibrillation relapse's history after ablation
* Pregnant and nursing women
* Patients refusal.
18 Years
ALL
No
Sponsors
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Hospices Civils de Lyon
OTHER
Responsible Party
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Principal Investigators
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Pierre Lantelme
Role: PRINCIPAL_INVESTIGATOR
Hospices Civils de Lyon - Hôpital de la Croix rousse
Locations
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Hospices Civils de Lyon - Hôpital de la Croix Rousse
Lyon, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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69HCL17_0508
Identifier Type: -
Identifier Source: org_study_id
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