Genetic Basis of Pacing-induced Cardiomyopathy

NCT ID: NCT03317964

Last Updated: 2025-06-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

153 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-16

Study Completion Date

2025-06-19

Brief Summary

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The purpose of this study is to collect a saliva sample from patients with a pacemaker to study genes involved in cardiomyopathy, a condition where the heart muscle is abnormal.

Detailed Description

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DNA will be extracted from the saliva to test for changes in genes related to cardiomyopathy.

Conditions

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Pacemaker, Artificial Cardiomyopathies

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Saliva - cardiomyopathy

Saliva sample for genetic testing from subjects who developed cardiomyopathy

Saliva sample

Intervention Type OTHER

Extract sample of saliva only once

Saliva - no cardiomyopathy

Saliva sample for genetic testing from subjects who do not have cariomyopathy

Saliva sample

Intervention Type OTHER

Extract sample of saliva only once

Interventions

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Saliva sample

Extract sample of saliva only once

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients who have been assessed for cardiomyopathy

Exclusion Criteria

* Patients who do not have adequate follow up care to determine if they do or do not have cardiomyopathy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The Guthrie Clinic

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pramod Deshmukh, MD

Role: PRINCIPAL_INVESTIGATOR

The Guthrie Clinic

Locations

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Robert Packer Hospital

Sayre, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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1706-34

Identifier Type: -

Identifier Source: org_study_id

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