Cost-Effectiveness of Routine Follow-up Visits in Patients With a Pacemaker: The Followpace Study

NCT ID: NCT00135174

Last Updated: 2008-06-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1526 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-09-30

Study Completion Date

2012-01-31

Brief Summary

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The overall objective of the study is to quantify the true prognostic value and cost-effectiveness of routine follow-up visits in patients who receive an approved pacemaker of any type for the first time.

Detailed Description

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Specific objectives :

* To determine the incidence of complications occurring in the first year after implantation of a pacemaker.
* To determine the quality of life at one year after pacemaker implantation in comparison with the quality of life before implantation.
* To determine which baseline (patient and pacemaker related) characteristics measured during implantation are prognostic predictors for the occurrence of complications and quality of life after one year.
* To determine which characteristics measured during follow-up visits truly have added predictive value, and to what extent.
* To determine to what extent responsibilities for pacemaker check-up can be safely delegated to non-cardiologists (e.g. pacemaker technicians or manufacturers' delegates).

Conditions

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Arrhythmia Heart Diseases

Keywords

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Pacemaker routine follow-up complications Quality of Life

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Each patient aged 18 years or over receiving a pacemaker for the first time in one of the participating Dutch pacemaker implanting centers, is a potential candidate for the study.

Exclusion Criteria

* Patients are not eligible if they refuse to sign informed consent on use of personal medical data.
* Patients who are taking any investigational (new) drug or have a non-approved or investigational pacemaker system which requires unusual follow-up regarding the pacemaker
* Patients having diseases that are likely to cause death or significant morbidity during the study period such as neoplasia and immune, infectious or degenerative diseases will be excluded.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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College of Health Insurers/Society of Academic Hospitals,

UNKNOWN

Sponsor Role collaborator

Dutch Working Group on Cardiac Pacing,

UNKNOWN

Sponsor Role collaborator

Foundation Pacemaker Registry in The Netherlands,

UNKNOWN

Sponsor Role collaborator

UMC Utrecht

OTHER

Sponsor Role lead

Responsible Party

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Julius Center for Health Sciences and Primary Care

Principal Investigators

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Norbert van Hemel, M.D.

Role: STUDY_CHAIR

University of Utrecht, Julius Center for Primary Care and Health Sciences

Karel G Moons, PhD

Role: STUDY_CHAIR

University of Utrecht, Julius Center for Primary Care and Health Sciences

Diederick E Grobbee, M.D.

Role: STUDY_CHAIR

University of Utrecht, Julius Center for Primary Care and Health Sciences

Locations

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Julius Center for Primary Care and Health Sciences, University Medical Center Utrecht

Utrecht, Utrecht, Netherlands

Site Status

Countries

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Netherlands

References

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Udo EO, van Hemel NM, Zuithoff NP, Doevendans PA, Moons KG. Risk of heart failure- and cardiac death gradually increases with more right ventricular pacing. Int J Cardiol. 2015 Apr 15;185:95-100. doi: 10.1016/j.ijcard.2015.03.053. Epub 2015 Mar 5.

Reference Type DERIVED
PMID: 25804349 (View on PubMed)

Udo EO, van Hemel NM, Zuithoff NP, Doevendans PA, Moons KG. Prognosis of the bradycardia pacemaker recipient assessed at first implantation: a nationwide cohort study. Heart. 2013 Nov;99(21):1573-8. doi: 10.1136/heartjnl-2013-304445. Epub 2013 Aug 22.

Reference Type DERIVED
PMID: 23969476 (View on PubMed)

Udo EO, van Hemel NM, Zuithoff NP, Nijboer H, Taks W, Doevendans PA, Moons KG. Long term quality-of-life in patients with bradycardia pacemaker implantation. Int J Cardiol. 2013 Oct 3;168(3):2159-63. doi: 10.1016/j.ijcard.2013.01.253. Epub 2013 Feb 28.

Reference Type DERIVED
PMID: 23453871 (View on PubMed)

Udo EO, van Hemel NM, Zuithoff NP, Dijk WA, Hooijschuur CA, Doevendans PA, Moons KG. Pacemaker follow-up: are the latest guidelines in line with modern pacemaker practice? Europace. 2013 Feb;15(2):243-51. doi: 10.1093/europace/eus310. Epub 2012 Oct 24.

Reference Type DERIVED
PMID: 23097223 (View on PubMed)

Udo EO, van Hemel NM, Zuithoff NP, Kelder JC, Crommentuijn HA, Koopman-Verhagen AM, Voskuil T, Doevendans PA, Moons KG. Long-term outcome of cardiac pacing in octogenarians and nonagenarians. Europace. 2012 Apr;14(4):502-8. doi: 10.1093/europace/eur329. Epub 2011 Oct 23.

Reference Type DERIVED
PMID: 22024601 (View on PubMed)

Related Links

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http://www.juliuscenter.nl

Webpage with information on study center.

http://www.followpace.nl

Electronic CRF pages and entire protocol can be viewed here.

Other Identifiers

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CVZ/VAZ 01236

Identifier Type: -

Identifier Source: org_study_id