Podocyturia as Predictive Factor for Pre-eclampsia

NCT ID: NCT03316430

Last Updated: 2022-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-05-15

Study Completion Date

2021-12-07

Brief Summary

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Pre-eclampsia is an hypertensive disorder appearing during pregnancy, inducing serious maternal, fetal and neonatal mortality and morbidity. Podocyn could be identified in the urine, before proteinuria, a key element in the diagnostic of pre-eclampsia. Preventive treatment using aspirin could be administrated in early pregnancy. We hypothesized that podocyturia could be an early indicator of preeclampsia. This is a prospective, non-interventional, monocentric study.

Detailed Description

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Conditions

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Pre-Eclampsia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients

Patients coming before 16 weeks of gestation at their first planned prenatal visit at the Hôpital Femme Mère Enfant, who planned to deliver at the Hôpital Femme Mère Enfant

Podocyturia quantification

Intervention Type OTHER

Podocyturia quantification at first planned prenatal care visit before 16 weeks of gestation

Interventions

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Podocyturia quantification

Podocyturia quantification at first planned prenatal care visit before 16 weeks of gestation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* women aged 18 years or more
* single pregnancy
* first planned prenatal visit before 16 weeks of gestation
* planned delivery at Hôpital Femme Mère Enfant in Lyon, France
* patient receiving information and non opposition to participate

Exclusion Criteria

* multiple pregnancy
* pregnancy stopped
* antecedent of nephropathy
* inability to understand information provided
* prisoner or under administrative supervision
* fetal malformation, chromosomal anomalies
* preterm delivery for other reason that any hypertensive disorder of pregnancy or Intrauterine growth restriction
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Hospices Civils de Lyon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of obstetrics, Femme Mère Enfant Hospital, Lyon, France

Bron, , France

Site Status

Countries

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France

Other Identifiers

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69HCL17_0516

Identifier Type: -

Identifier Source: org_study_id

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