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Study of the Physiology of Pre-eclampsia and Vascular IUGR With Constitution of a Biological Collection

NCT ID: NCT03626233

Last Updated: 2022-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-06

Study Completion Date

2024-04-30

Brief Summary

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Preeclampsia and intrauterine growth retardation (IUGR) are serious and frequent pathologies, specific to pregnancy. They represent 70 000 new cases a year, or 9% of pregnancies and cause 50,000 premature births per year in France. The consequences in terms of morbidity and perinatal morbidity and the medical and economic costs make it an issue public health. Pre-eclampsia associates maternal hypertension with dysfunction kidney. There is no cure for pre-eclampsia or IUGR vascular during pregnancy. These pathologies invariably evolve towards a maternal and / or fetal aggravation sometimes very fast. Primary prevention and secondary education and screening for these pathologies are still insufficient. A better understanding of the pathophysiology of these placental vascular pathologies is necessary for the development of supported medical, obstetric and pediatric that will improve the state of health maternal and neonatal

Detailed Description

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Conditions

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Pre-Eclampsia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Vascular group

Pregnant women with vascular pathology

collect of placenta, blood and urinary samples at delivery

Intervention Type OTHER

collect of placenta, blood and urinary samples at delivery

Control group

* Pregnancy without any vascular complication
* Delivery before or after 37 weeks of gestation (GW)
* In case of delivery after 37GW: birth by cesarean delivery

collect of placenta, blood and urinary samples at delivery

Intervention Type OTHER

collect of placenta, blood and urinary samples at delivery

Interventions

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collect of placenta, blood and urinary samples at delivery

collect of placenta, blood and urinary samples at delivery

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* pregnant women
* With or without vascular pathology

Exclusion Criteria

* refusal to participate
* multiple pregnancy
* major fetal malformation diagnosed during pregnancy follow-up
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Intercommunal Creteil

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Edouard Lecarpentier, MD PhD

Role: PRINCIPAL_INVESTIGATOR

CHI CRETEIL

Locations

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CHi Creteil

Créteil, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Diane REDEL

Role: CONTACT

Phone: 145175530

Email: [email protected]

camille Jung

Role: CONTACT

Phone: 157022268

Email: [email protected]

Facility Contacts

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Diane REDEL

Role: primary

Other Identifiers

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CPVP

Identifier Type: -

Identifier Source: org_study_id