Study Results
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View full resultsBasic Information
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COMPLETED
281 participants
OBSERVATIONAL
2018-02-01
2021-08-01
Brief Summary
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Detailed Description
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2\. Analyze the urine of 100 smokers and 100 non-smokers from each of these groups for mercapturic acids of acrolein and crotonaldehyde, as well as total nicotine equivalents and total NNAL (smokers only). These data will provide critical information relevant to the high risk of Native Hawaiians for lung cancer, and in relationship to the DNA adduct measurements of Specific Aim 1.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Native Hawaiian cigarette smokers
oral cell DNA adducts
oral cell DNA adducts
oral cells will be collected, DNA isolated, and analyzed for adducts
White (European Americans) cigarette smokers
oral cell DNA adducts
oral cell DNA adducts
oral cells will be collected, DNA isolated, and analyzed for adducts
Japanese American cigarette smokers
oral cell DNA adducts
oral cell DNA adducts
oral cells will be collected, DNA isolated, and analyzed for adducts
Interventions
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oral cell DNA adducts
oral cells will be collected, DNA isolated, and analyzed for adducts
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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University of Hawaii
OTHER
University of Minnesota
OTHER
Responsible Party
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Principal Investigators
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Stepehn Hecht, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Minnesota
Locations
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Tobacco Use Research Center
Minneapolis, Minnesota, United States
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Document Type: Informed Consent Form
Other Identifiers
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2017NTLS019
Identifier Type: -
Identifier Source: org_study_id
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