"Beverage Hydration Index" of Commercial Therapeutic Beverages

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

46 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-02-17

Study Completion Date

2017-04-14

Brief Summary

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The "beverage hydration index" (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric. Our purpose was to assess the BHI of beverages never previously tested, including an amino acid-based oral rehydration solution (AA-ORS), a glucose-containing ORS (G-ORS) and a sports drink (SD) compared to water (control).

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Detailed Description

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The "Beverage Hydration Index" (BHI) was created to assess the degree to which beverages "hydrate", by measuring fluid retention after ingesting a 1 liter bolus and comparing it to water. Drinks with carbohydrates and electrolytes would traditionally be expected to score higher on the BHI due to glucose-sodium cotransport at the gut and osmolality approaching isotonicity with blood. One recent study reported that an oral rehydration solution (ORS) scored better than water, but a "sports drink" did not. No "optimal" BHI beverage composition has been described, nor has an optimal osmolality. Recently, a hypotonic amino acid-based rehydration beverage was developed to take advantage of amino acid-sodium cotransport, thus obviating the need for carbohydrate. However, the BHI of this beverage has not yet been assessed. The purpose of this investigation was to assess the hydration potential of this novel beverage in comparison to a commercially available carbohydrate-containing sports drink and oral rehydration solution.

Conditions

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Healthy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Repeated-measures design with generalized latin square arrangement. Each participant will complete 4 separate trials.

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Beverage Hydration Index of beverages

Subjects will consume 4 different beverages to obtain the beverage hydration index.

Group Type EXPERIMENTAL

enterade

Intervention Type OTHER

Subjects will consume enterade, which is an amino acid-based oral rehydration solution.

Pedialyte

Intervention Type OTHER

Subjects will consume Pedialyte

Gatorade

Intervention Type OTHER

Subjects will consume Gatorade

Water

Intervention Type OTHER

Subjects will consume water as the control beverage

Interventions

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enterade

Subjects will consume enterade, which is an amino acid-based oral rehydration solution.

Intervention Type OTHER

Pedialyte

Subjects will consume Pedialyte

Intervention Type OTHER

Gatorade

Subjects will consume Gatorade

Intervention Type OTHER

Water

Subjects will consume water as the control beverage

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy male or female
* Aged 18-35
* BMI 18-27 kg/m2
* No known cardiovascular, renal or metabolic disease
* Moderately active
* Moderate alcohol use

Exclusion Criteria

* Overweight or obese (BMI \>27 kg/m2)

* Competitive athletes during competition season
* Current or former cardiovascular, renal or metabolic disease
* Habitual consumption of alcohol (\>21 units/week) or regular (\>1/week) high (10 units) intake\*
* History of psychiatric illness
* Actively seeking to gain or lose weight
* Currently taking prescribed medication

* Example, a 750 ml bottle of wine at 12% ABV contains 0.750 Liters \* 12 = 9 units

Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes