/Autism Spectrum Disorder(ASD)Hearing Abnormalities Study

NCT ID: NCT03252392

Last Updated: 2017-08-17

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 80 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2017-10-01
• Study Completion Date: 2020-10-01

Brief Summary

Co morbidity rates of hearing loss in children with autism spectrum disorder are high and increasing.

Investigators are aiming to:

1. evaluate peripheral auditory and brain stem auditory function in children with autism spectrum disorder.

2. compare communication capabilities in autistic children having hearing abnormalities and autistic children with normal hearing.

Detailed Description

Full audiological evaluation is carried out to all participants including:

• pure tone and speech audiometry.
• Tympanometry and acoustic reflex threshold evaluation.
• Threshold auditory brain stem response for threshold determination in non co operative children not respond to pure tone,speech audiometry.
• Auditory brain stem response for neuro-otologic diagnosis.
• Transient evoked otoacoustic emissions in children proved to have normal hearing to detect minimal cochlear affection .
• Transient evoked otoacoustic emissions with contralateral masking. Communication evaluation is carried out to all participants using arabic language test(kotby et al,1995).

Investigators use childhood autism rating scale for (CARS) for diagnosis of autism spectrum disorder.

Conditions

Autism Spectrum Disorder

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

children with autism spectrum disorder

Children aged 3-12 years diagnosed to have mild to moderate autism spectrum disorder diagnosed by childhood autism spectrum disorder(CARS 35% or less)

No interventions assigned to this group

healthy non autistic age matched volunteers

children aged 3-12 years old never diagnosed to have autism spectrum disorder

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Children aged 3-12 years diagnosed to have mild to moderate autism spectrum disorder diagnosed by childhood autism spectrum disorder(CARS 35% or less)

Exclusion Criteria

• children with otitis media with effusion.
• Associated neurological deficit .

• Minimum Eligible Age: 3 Years
• Maximum Eligible Age: 12 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

weaam noaman mohamed

Principal invistigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Other Identifiers

IRB17200055

Identifier Type: -

Identifier Source: org_study_id