Crystalloids for AKI in Shock Patients

NCT ID: NCT03188614

Last Updated: 2017-06-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-01

Study Completion Date

2018-10-01

Brief Summary

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Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia, which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.

Detailed Description

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Conditions

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Shock

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Normal saline group

Shock patients who resuscitated with normal saline were enrolled between June, 2015-June.2016.

Group Type PLACEBO_COMPARATOR

Fluid resuscitation

Intervention Type DRUG

The placebo group is resuscitated with normal saline, the experimental group is resuscitated with balanced fluid.

Balanced solution group

Shock patients who resuscitated with balanced solution were enrolled after June, 2016.

Group Type EXPERIMENTAL

Fluid resuscitation

Intervention Type DRUG

The placebo group is resuscitated with normal saline, the experimental group is resuscitated with balanced fluid.

Interventions

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Fluid resuscitation

The placebo group is resuscitated with normal saline, the experimental group is resuscitated with balanced fluid.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Shock patients

Exclusion Criteria

* History of chronic renal failure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Southeast University, China

OTHER

Sponsor Role lead

Responsible Party

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Jingyuan,Xu

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Haibo Qiu, Doctor

Role: PRINCIPAL_INVESTIGATOR

Southeast University

Central Contacts

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Jingyuan Xu, Docotor

Role: CONTACT

13851417209

Other Identifiers

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2017ZDSYLL018P

Identifier Type: -

Identifier Source: org_study_id

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