The Relationship Between Normal Saline Infusion and Acute Kidney Injury in Heat Stroke
NCT ID: NCT05921695
Last Updated: 2024-09-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
190 participants
INTERVENTIONAL
2023-05-28
2026-03-31
Brief Summary
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Participants will receive a free normal saline infusion during the emergency department according to the study design, or a restricted normal saline infusion while using sodium lactate Ringer's instead.
Researchers will compare the normal saline infusion group and sodium lactate Ringer's group to see if limiting the amount of normal saline infusion during emergency department can lower the incidence of acute kidney injury and mortality in patients with heat stroke.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
SUPPORTIVE_CARE
NONE
Study Groups
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Normal Saline infusion group
During the emergency department, the normal saline infusion was not restricted.
Normal Saline infusion and Ringer lactate infusion
The heat stroke patients will be infused with different chlorine concentrations fluid during the emergency department.
Ringer lactate infusion group
Use ringer lactate or other balanced crystallographic solution instead of normal saline. Strictly limit the amount of normal saline infusion. Normal saline will only be infused by medical advice if the patient has hypochloremia or needs saline as solvent.
Normal Saline infusion and Ringer lactate infusion
The heat stroke patients will be infused with different chlorine concentrations fluid during the emergency department.
Interventions
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Normal Saline infusion and Ringer lactate infusion
The heat stroke patients will be infused with different chlorine concentrations fluid during the emergency department.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* diagnosed as heat stroke
* Informed consent from patients or family members.
Exclusion Criteria
* transferred from another hospital
* with original end-stage renal disease or dialysis
* with severe organ damage
* pregnant women
18 Years
ALL
No
Sponsors
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Yiwu Central Hospital
OTHER
Jinhua People's Hospital
OTHER
Jinhua Municipal Central Hospital
OTHER
Dongyang People's Hospital
OTHER
Lanxi People's Hospital
OTHER
Second Affiliated Hospital, School of Medicine, Zhejiang University
OTHER
Responsible Party
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Principal Investigators
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Lan Chen, PHD
Role: PRINCIPAL_INVESTIGATOR
Second Affiliated Hospital, School of Medicine, Zhejiang University
Locations
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YongKang First People's Hospital
Guli, Zhejiang, China
Yiwu Central Hospital
Yiwu, Zhejiang, China
Dongyang People's Hospital
Dongyang, , China
The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, , China
Jinhua Municipal Central Hospital
Jinhua, , China
Jinhua People's Hospital
Jinhua, , China
Lanxi People's Hospital
Lanxi, , China
Countries
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Central Contacts
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Facility Contacts
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Shuying Xu
Role: primary
Sunying Wu
Role: primary
Xiaoling Yang
Role: primary
Other Identifiers
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20230506
Identifier Type: -
Identifier Source: org_study_id
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