Effect of Cumulative Chloride Dose on Development of Acute Kidney Injury in Critically Ill Children

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2013-07-31

Study Completion Date

2015-06-30

Brief Summary

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The investigators would like to investigate the effect of chloride dosing on the development of acute kidney injury in critically ill patients. The investigators hypothesis is that administering intravenous fluids with higher chloride content are more likely to lead to acute kidney injury.

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Detailed Description

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Retrospective chart review from 2008-2012 evaluating chloride dosing and serum chloride levels and their effects on acute kidney injury in the pediatric ICU. Patients will be included for the first seven days of their PICU stay.

Conditions

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Acute Kidney Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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High Chloride Dose

Patients receiving high dosing of chloride

No interventions assigned to this group

Low Chloride Dose

Patients receiving low dosing of chloride

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* age less than 18 years
* PICU admitting diagnosis of sepsis, respiratory failure, or hepatic failure.

Exclusion Criteria

* hyponatremia or hypernatremia at PICU admission
* preexisting diagnosis of End-stage renal disease or renal transplant
* presence of neurologic comorbidities.

Minimum Eligible Age

1 Month

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No