Anticholinergic Risk Scale and Resource Use After Elective Noncardiac Surgery

NCT ID: NCT03151616

Last Updated: 2025-01-10

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

244976 participants

Study Classification

OBSERVATIONAL

Study Start Date

2003-04-01

Study Completion Date

2014-03-31

Brief Summary

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This study investigates the association of preoperative anticholinergic medication exposure with healthcare resource utilization in a population-based sample of older patients enrolled in a universal pharmacare program

Detailed Description

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Multilevel multivariable regression analysis will be used to investigate the adjusted association between preoperative Anticholinergic Risk Scale and postoperative healthcare resource utilization. Sensitivity analyses will be used to evaluate the robustness of the primary analysis.

Conditions

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Length of Stay Anti Cholinergics Surgical Procedure, Operative Aged Epidemiology

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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No anticholinergic exposure

People with an anticholinergic risk scale score of 0

No interventions assigned to this group

Moderate anticholinergic exposure

People with an anticholinergic risk scale score of 1-2

anticholinergic risk scale

Intervention Type OTHER

Risk summation scale for grading and studying anticholinergic medication exposure

High anticholinergic exposure

People with an anticholinergic risk scale score of \>=3

anticholinergic risk scale

Intervention Type OTHER

Risk summation scale for grading and studying anticholinergic medication exposure

Interventions

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anticholinergic risk scale

Risk summation scale for grading and studying anticholinergic medication exposure

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* at least 66 years old on the day of surgery
* Intermediate to high risk elective noncardiac surgery

Exclusion Criteria

\-
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ottawa Hospital Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Dan McIsaac

Associate Scientist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ottawa Hospital Research Institute

Ottawa, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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DM6

Identifier Type: -

Identifier Source: org_study_id

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