Mechanisms of Anxiety and Depression Study

NCT ID: NCT03135756

Last Updated: 2018-05-11

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 63 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2015-03-19
• Study Completion Date: 2018-03-14

Brief Summary

Eligible participants will come in for three separate visits in which they will be interviewed, perform a variety of tasks, and undergo a non-invasive MRI scan. The investigators anticipate that (1) participants with anxiety and depression will likely perform differently than the healthy controls on cognitive tasks, (2) participants with anxiety and depression will likely show differences in brain functionality compared to the healthy controls, and (3) depression and anxiety likely share some underlying mechanisms.

Detailed Description

In order to determine eligibility, a brief phone screen lasting approximately 15 minutes will be conducted. If participants are eligible, they will be asked to come in for three separate visits. During the first visit, participants will complete questionnaires as well as a structured interview with one of the study's staff members at Palo Alto University in Los Altos. During the second visit, participants would come to Palo Alto University in Los Altos and complete questionnaires as well as a testing session involving various tasks. During the third visit, participants would undergo a non-invasive brain scan in which participants would complete a task as well as various questionnaires at Stanford University in Stanford.

The investigators have flexible hours and can work around participants' schedules! To inquire more about participation, participants can either email the investigators at paloalto.study@gmail.com or call the investigators at (650) 417-2000 ext. 3642

Conditions

Depression; Anxiety

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Depression and anxiety symptoms

No interventions assigned to this group

Healthy controls

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Right-handed
• Healthy with no medical conditions OR have a history of anxiety and/or depression
• Ability to travel to both Palo Alto University and Stanford University

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Palo Alto University

OTHER

Sponsor Role: lead

Responsible Party

Stacie Warren, Ph.D.

Primary Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Stacie Warren, PhD

Role: PRINCIPAL_INVESTIGATOR

Palo Alto University

Locations

Palo Alto University

Los Altos, California, United States

Stanford University

Stanford, California, United States

Countries

United States

Other Identifiers

15-003-H

Identifier Type: -

Identifier Source: org_study_id