Electronic Alert System for Improving Thromboprophylaxis in Hospitalized Medical Patients

NCT ID: NCT03124017

Last Updated: 2017-04-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1756 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-03-31

Study Completion Date

2016-06-30

Brief Summary

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The investigators aim to investigate whether a computer-based alert system in the electronic patient chart and order entry system using the Geneva Risk Score as clinical decision support tool to estimate the risk of venous thromboembolism improves the rate of appropriate thromboprophylaxis among hospitalized medical patients.

Detailed Description

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The use of thromboprophylaxis among acutely ill hospitalized medical patients remains inconsistent. The present study aims to improve the use of appropriate thromboprophylaxis by implementing a computer-based alert system combined with a Geneva Risk Score calculation tool in the electronic patient chart and order entry system. Consecutive acutely ill medical patients without indication for therapeutic anticoagulation or ongoing therapeutic anticoagulant treatment admitted to the medical wards of the University Hospital Bern, Switzerland, will be randomized in a 1:1 fashion to the alert group in which an alert and the Geneva Risk Score calculation tool will be issued in the electronic patient chart or to the control group in which no alert will be issued. The primary endpoint is the rate of appropriate thromboprophylaxis during hospital stay.

Conditions

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Venous Thromboembolism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Alert Group

Electronic alert and the Geneva Risk Score calculation tool issued in the electronic patient chart

Group Type EXPERIMENTAL

Electronic alert and the Geneva Risk Score calculation tool issued in the electronic patient chart

Intervention Type OTHER

Control Group

No electronic alert and no Geneva Risk Score calculation tool issued in the electronic patient chart

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Electronic alert and the Geneva Risk Score calculation tool issued in the electronic patient chart

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Acutely ill medical patients admitted to medical wards

Exclusion Criteria

* Indication for therapeutic anticoagulation or ongoing therapeutic anticoagulant treatment
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Insel Gruppe AG, University Hospital Bern

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nils Kucher, Prof. M.D.

Role: PRINCIPAL_INVESTIGATOR

Swiss Cardiovascular Center, Division of Vascular Medicine, University of Bern, University Hospital Bern, Bern, Switzerland

Locations

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Swiss Cardiovascular Center, Inselspital, University of Bern

Bern, , Switzerland

Site Status

Countries

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Switzerland

References

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Spirk D, Stuck AK, Hager A, Engelberger RP, Aujesky D, Kucher N. Electronic alert system for improving appropriate thromboprophylaxis in hospitalized medical patients: a randomized controlled trial. J Thromb Haemost. 2017 Nov;15(11):2138-2146. doi: 10.1111/jth.13812. Epub 2017 Sep 20.

Reference Type DERIVED
PMID: 28836340 (View on PubMed)

Other Identifiers

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159/14

Identifier Type: -

Identifier Source: org_study_id

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