HILO-HF Registry: High Versus Low SpO2 Oxygen Therapy in Patients With Acute Heart Failure

NCT ID: NCT03110042

Last Updated: 2019-04-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2016-11-30
• Study Completion Date: 2019-04-30

Brief Summary

The HILO-HF Registry is a single centre registry that will be performed to provide information on the usual baseline oxygen saturation (SpO2) in patients presenting to ED with a primary ED diagnosis of AHF

Conditions

Acute Heart Failure

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Observational Cohort

All patients will receive usual standard of care with the heart failure management including the routine supplemental oxygen therapy.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Patients >40 years of age presenting to the ED with AHF
• With or without tested BNP
• With or without admission to hospital for treatment of HF\
• Patients must be recruited within the first 24 hours of presenting to the ED.

Exclusion Criteria

• Patients on home oxygen
• Patients with known prior hypercapnic failure (PaCO2>50 mmHg)
• Asthma
• Primary pulmonary hypertension
• Patients requiring urgent positive pressure ventilation or intubation or on >10 L/min oxygen

• Minimum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Alberta

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Justin Ezekowitz, MD

Role: PRINCIPAL_INVESTIGATOR

University of Alberta

Locations

University of Alberta Hospital / Mazankowski Alberta Heart Institute

Edmonton, Alberta, Canada

Countries

Canada

Other Identifiers

HILO-HF Registry

Identifier Type: -

Identifier Source: org_study_id