A Multicenter Registry Study of Aneurysmal SAH

NCT ID: NCT03094975

Last Updated: 2017-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-07-01

Study Completion Date

2019-12-30

Brief Summary

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Firstly, this study aims at clarifying the current situation of Emergency treatment of aneurysmal subarachnoid hemorrhage (SAH) in China, and analyzing the influencing factors contributing to transport delay, so as to improve the efficiency of emergency treatment; Secondly, comparison and analysis of different surgical treatment of aneurysmal SAH would be undertook, so as to improve the diagnosis and treatment of aneurysmal SAH.

Detailed Description

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Conditions

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Subarachnoid Hemorrhage, Aneurysmal Time Delay

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients presented with subarachnoid hemorrhage on CT or lumbar puncture.
* the intracranial hemorrhage was caused by rupture of aneurysm and was confirmed on CTA、MRA or DSA.
* patients willing to participate in this clinical trial and attach to regular follow up.

Exclusion Criteria

* intracranial aneurysm correlating to AVM.
* dissection, false, traumatic and infectious aneurysms.
* the rupture of the aneurysm can not be confirmed on CTA、MRA or DSA.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jian-min Liu

OTHER

Sponsor Role lead

Responsible Party

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Jian-min Liu

Director

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Jianmin Liu, MD.

Role: PRINCIPAL_INVESTIGATOR

Changhai Hospital

Locations

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Changhai hospital

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Central Contacts

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Rui Zhao, MD.

Role: CONTACT

+86 13916728169

Xiaoxi Zhang, MD.

Role: CONTACT

+86 18801765148

References

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de Rooij NK, Linn FH, van der Plas JA, Algra A, Rinkel GJ. Incidence of subarachnoid haemorrhage: a systematic review with emphasis on region, age, gender and time trends. J Neurol Neurosurg Psychiatry. 2007 Dec;78(12):1365-72. doi: 10.1136/jnnp.2007.117655. Epub 2007 Apr 30.

Reference Type RESULT
PMID: 17470467 (View on PubMed)

Kozak N, Hayashi M. Trends in the incidence of subarachnoid hemorrhage in Akita Prefecture, Japan. J Neurosurg. 2007 Feb;106(2):234-8. doi: 10.3171/jns.2007.106.2.234.

Reference Type RESULT
PMID: 17410705 (View on PubMed)

Molyneux A, Kerr R, Stratton I, Sandercock P, Clarke M, Shrimpton J, Holman R; International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group. International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial. Lancet. 2002 Oct 26;360(9342):1267-74. doi: 10.1016/s0140-6736(02)11314-6.

Reference Type RESULT
PMID: 12414200 (View on PubMed)

Johnston SC, Selvin S, Gress DR. The burden, trends, and demographics of mortality from subarachnoid hemorrhage. Neurology. 1998 May;50(5):1413-8. doi: 10.1212/wnl.50.5.1413.

Reference Type RESULT
PMID: 9595997 (View on PubMed)

Bian LH, Liu YF, Nichols LT, Wang CX, Wang YL, Liu GF, Wang WJ, Zhao XQ. Epidemiology of subarachnoid hemorrhage, patterns of management, and outcomes in China: a hospital-based multicenter prospective study. CNS Neurosci Ther. 2012 Nov;18(11):895-902. doi: 10.1111/cns.12001. Epub 2012 Sep 12.

Reference Type RESULT
PMID: 22966850 (View on PubMed)

Cross DT 3rd, Tirschwell DL, Clark MA, Tuden D, Derdeyn CP, Moran CJ, Dacey RG Jr. Mortality rates after subarachnoid hemorrhage: variations according to hospital case volume in 18 states. J Neurosurg. 2003 Nov;99(5):810-7. doi: 10.3171/jns.2003.99.5.0810.

Reference Type RESULT
PMID: 14609158 (View on PubMed)

Shea AM, Reed SD, Curtis LH, Alexander MJ, Villani JJ, Schulman KA. Characteristics of nontraumatic subarachnoid hemorrhage in the United States in 2003. Neurosurgery. 2007 Dec;61(6):1131-7; discussion 1137-8. doi: 10.1227/01.neu.0000306090.30517.ae.

Reference Type RESULT
PMID: 18162891 (View on PubMed)

Li H, Pan R, Wang H, Rong X, Yin Z, Milgrom DP, Shi X, Tang Y, Peng Y. Clipping versus coiling for ruptured intracranial aneurysms: a systematic review and meta-analysis. Stroke. 2013 Jan;44(1):29-37. doi: 10.1161/STROKEAHA.112.663559. Epub 2012 Dec 13.

Reference Type RESULT
PMID: 23238862 (View on PubMed)

Darsaut TE, Raymond J. Barrow Ruptured Aneurysm Trial: 3-year results. J Neurosurg. 2013 Dec;119(6):1642-4. doi: 10.3171/2013.5.JNS13917. Epub 2013 Aug 30. No abstract available.

Reference Type RESULT
PMID: 23991842 (View on PubMed)

Dacks PA, Armstrong JJ, Brannan SK, Carman AJ, Green AM, Kirkman MS, Krakoff LR, Kuller LH, Launer LJ, Lovestone S, Merikle E, Neumann PJ, Rockwood K, Shineman DW, Stefanacci RG, Velentgas P, Viswanathan A, Whitmer RA, Williamson JD, Fillit HM. A call for comparative effectiveness research to learn whether routine clinical care decisions can protect from dementia and cognitive decline. Alzheimers Res Ther. 2016 Aug 20;8:33. doi: 10.1186/s13195-016-0200-3.

Reference Type RESULT
PMID: 27543171 (View on PubMed)

Other Identifiers

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CHEC2017-022

Identifier Type: -

Identifier Source: org_study_id

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