Retrospective Cohort Study of Intracerebral Hemorrhage

NCT ID: NCT04803292

Last Updated: 2021-03-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-01

Study Completion Date

2025-10-01

Brief Summary

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The investigators design a retrospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective, treatments and prognosis of Chinese hospitalized adult patients with intracerebral hemorrhage.

Detailed Description

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Intracerebral hemorrhage (ICH) remains a devastating disease with high mortality, yet few therapeutic managements have been proved effective. Large quantities of work needs to be done to fully delineate the prevalence and prognosis of ICH. Hence, the investigators design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective, treatments and prognosis of Chinese hospitalised adult patients with ICH.

Conditions

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Intracerebral Hemorrhage

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Second Affiliated Hospital, School of Medicine, Zhejiang University

a prospective cohort of patients of primary intracerebral hemorrhage in Second Affiliated Hospital, School of Medicine, Zhejiang University

No interventions assigned to this group

Second People's Hospital of Hangzhou City, Zhejiang Province

a prospective cohort of patients of primary intracerebral hemorrhage in Second People's Hospital of Hangzhou City, Zhejiang Province

No interventions assigned to this group

4th Affiliated Hospital, School of Medicine at Zhejiang University

a prospective cohort of patients of primary intracerebral hemorrhage in 4th Affiliated Hospital, School of Medicine at Zhejiang University

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Hospitalized patients over 18 years old of primary intracerebral hemorrhage.

Exclusion Criteria

1. patients of secondary intracerebral hemorrhage,such as hemorrhagic transformation of ischemic stroke, aneurysmal, cavernomas, arterio- venous malformations, central venous thrombosis, trauma-related, or tumor
2. isolated intraventricular hemorrhage or subarachnoid hemorrhage pregnant patients
3. unavailability to get complete blood cell samples and presenting contraindications or refusal to MRI
4. patients cannot be followed up for any reasons.
5. patients death in 24 hours
6. pregnant patients
7. surgical evacuation of hematoma
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Feng Gao, MD,PhD

Role: PRINCIPAL_INVESTIGATOR

Second Affiliated Hospital, School of Medicine, Zhejiang University

Locations

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2nd Affiliated Hospital, School of Medicine at Zhejiang University

Hangzhou, Zhejiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Feng Gao, MD,PhD

Role: CONTACT

13588451471

Lusha Tong, MD,PhD

Role: CONTACT

15868171218

Facility Contacts

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Feng Gao, MD,PhD

Role: primary

13588451471

References

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Jin Y, Huang YH, Chen YP, Zhang YD, Li J, Yang KC, Ye X, Jin LH, Wu J, Yuan CZ, Gao F, Tong LS. Combined effect of cortical superficial siderosis and cerebral microbleed on short-term and long-term outcomes after intracerebral haemorrhage. Stroke Vasc Neurol. 2024 Aug 27;9(4):429-438. doi: 10.1136/svn-2023-002439.

Reference Type DERIVED
PMID: 37949481 (View on PubMed)

Jin YJ, Li JW, Wu J, Huang YH, Yang KC, An HN, Yuan CZ, Gao F, Tong LS. Cortical superficial siderosis, hematoma volume, and outcomes after intracerebral hemorrhage: a mediation analysis. Front Neurol. 2023 May 5;14:1122744. doi: 10.3389/fneur.2023.1122744. eCollection 2023.

Reference Type DERIVED
PMID: 37213900 (View on PubMed)

Li J, Shen D, Zhou Y, Jin Y, Jin L, Ye X, Tong L, Gao F. Underlying microangiopathy and functional outcome of simultaneous multiple intracerebral hemorrhage. Front Aging Neurosci. 2022 Nov 8;14:1000573. doi: 10.3389/fnagi.2022.1000573. eCollection 2022.

Reference Type DERIVED
PMID: 36425320 (View on PubMed)

Other Identifiers

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I20200011153

Identifier Type: -

Identifier Source: org_study_id

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