Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group
NCT ID: NCT04945603
Last Updated: 2023-11-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
800 participants
OBSERVATIONAL
2021-05-25
2028-12-31
Brief Summary
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The search for outcome predictors is going to be subdivided into three main research areas:
1. outcome predictors in the emergency department (so called "early brain injury phase").
2. outcome predictors in the neurocritical care unit (so called "delayed brain injury phase").
3. Treatment strategies. Two other areas of research are identified: delayed cerebral ischemia (incidence, treatment, predictors, impact on outcome) and long term follow-up (recent evidences suggest that there may be a non-negligible proportion of poor grade subarachnoid hemorrhage patients who may benefit from substantial improvement at long-term (after 6-12 months of follow-up).
Detailed Description
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Conditions
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Study Design
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COHORT
OTHER
Study Groups
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Poor Grade Subarachnoid Hemorrhage
All patients (prospective and retrospective) included will have to present a subarachnoid hemorrhage defined poor grade according to the WFNS scale due to the rupture of an intracranial aneurysm.
The patients are managed according to both most recent international guidelines on the specific disease (Stroke, May 2012) and according to national and institutional guidelines/protocols.
Standard management according to international/national guidelines
Standard management according to international/national guidelines. Observational study
Interventions
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Standard management according to international/national guidelines
Standard management according to international/national guidelines. Observational study
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Pregnant or breast-feeding patients.
* Aneurysmal subarachnoid hemorrhage due to trauma or vascular malformations other than cerebral aneurysms.
18 Years
ALL
No
Sponsors
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Azienda Ospedaliera Universitaria Integrata Verona
OTHER
Azienda Ospedaliero-Universitaria di Parma
OTHER
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
OTHER
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
OTHER
A.O. Ospedale Papa Giovanni XXIII
OTHER
ASL Taranto
OTHER
Ospedale V. Fazzi
OTHER
IRCCS Istituto delle Scienze Neurologiche di Bologna
OTHER
Azienda Ospedaliero Universitaria Maggiore della Carita
OTHER
IRCCS San Raffaele
OTHER
Responsible Party
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Pietro Panni
Principal Investigator
Principal Investigators
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Pietro Panni, P.I., M.D.
Role: PRINCIPAL_INVESTIGATOR
Department of Neuroradiology, Department of Neurosurgery
Locations
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ASST Ospedale Papa Giovanni XXIII
Bergamo, , Italy
IRCCS Bellaria
Bologna, , Italy
Azienda Ospedaliera Spedali Civili
Brescia, , Italy
Ospedale Vito Fazzi
Lecce, , Italy
IRCCS San Raffaele
Milan, , Italy
Ospedale Maggiore della Città di Novara
Novara, , Italy
Azienda Ospedaliero-Universitaria di Parma
Parma, , Italy
Policlinico Universitario Agostino Gemelli
Roma, , Italy
Ospedale Santissima Annunziata
Taranto, , Italy
Azienda Ospedaliera Universitaria Integrata
Verona, , Italy
Countries
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Central Contacts
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Facility Contacts
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References
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Panni P, Ambrosi A; POGASH (Poor Grade Aneurysmal Subarachnoid Hemorrhage) Investigators. In Reply: Clinical Impact and Predictors of Aneurysmal Rebleeding in Poor-Grade Subarachnoid Hemorrhage: Results From the National POGASH Registry. Neurosurgery. 2023 Dec 1;93(6):e174-e176. doi: 10.1227/neu.0000000000002691. Epub 2023 Sep 21. No abstract available.
Panni P, Riccio L, Cao R, Pedicelli A, Marchese E, Caricato A, Feletti A, Testa M, Zanatta P, Gitti N, Piva S, Mardighian D, Semeraro V, Nardin G, Lozupone E, Paiano G, Picetti E, Montanaro V, Petranca M, Bortolotti C, Scibilia A, Cirillo L, Lanterna AL, Ambrosi A, Mortini P, Beretta L, Falini A. Clinical Impact and Predictors of Aneurysmal Rebleeding in Poor-Grade Subarachnoid Hemorrhage: Results From the National POGASH Registry. Neurosurgery. 2023 Sep 1;93(3):636-645. doi: 10.1227/neu.0000000000002467. Epub 2023 Apr 3.
Other Identifiers
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POGASH
Identifier Type: -
Identifier Source: org_study_id