Quantitative Sensory Testing in Subjects With Sensitive Skin or Not

NCT ID: NCT03081403

Last Updated: 2025-02-04

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 42 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-04-14
• Study Completion Date: 2017-10-27

Brief Summary

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin.

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Detailed Description

Sensitive skin is a common problem, with 50% of women and 30% of men in Europe feel they have sensitive skin. A sensitive skin is characterized by the occurrence of tingling sensations, tightness, heat, burning, itching or pain triggered by non pathogenic factors such as wind, heat, cold, water , cosmetics, toiletries, stress...

The Quantitative sensory testing (QST) is a physico-psychic method that uses gradients stimuli of different modalities to measure a subjective somatosensory response. This allows to characterize sensory dysfunction by assessing the participation of small and large nerve fibers.

The aim of this project is to characterize the presence or absence of a neurological disorder in patients with sensitive skin. This discovery would be a decisive argument to reinforce the suspicion that sensitive skins is linked to a small fiber neuropathy.

Conditions

Sensitive Skin

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Subjects with sensitive skin

Subjects with a score greater than 50 on the sensitive scale

Group Type: OTHER

Quantitative Sensory Testing

Intervention Type: DEVICE

Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

Subjects without sensitive skin

Subjects with result lower than 20 on the sensitive scale

Group Type: OTHER

Quantitative Sensory Testing

Intervention Type: DEVICE

Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

Interventions

Quantitative Sensory Testing

Study of detection thresholds of vibration, cold and pain related to the heat in the dominant hand of the subjects through the QST.

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Age: between 20 and 60 years
• Cooperating patient
• Informed and written consent of the subject
• Affiliated to the social security
• For subjects with sensitive skin:

subjects with a score greater than 50 on the scale sensitive scale

• To control subjects: subjects with result of less than 20 sensitive to the scale scale

Exclusion Criteria

• Adults subject with legal protection
• Subject in a social institution.
• Subject with major cognitive or psychiatric disorders
• Subject with pathological use of alcohol or consumption of another drug.
• Subject with skin involvement of the back of the dominant hand or malformation.
• Known sensitive neuropathy
• Pregnant woman
• Subject receiving medical treatment which may interfere with the results.
• Subject with treatment in the back of the dominant hand.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University Hospital, Brest

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

CHRU de Brest

Brest, , France

Countries

France

Other Identifiers

SENSISKIN 29CRB16.0100

Identifier Type: -

Identifier Source: org_study_id