Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index

NCT ID: NCT03062748

Last Updated: 2025-04-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

196 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-03-01

Study Completion Date

2026-12-31

Brief Summary

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The purpose of the study is to compare the relative contribution of systemic inflammation vs. Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting cardiovascular and metabolic aberrations associated with mild-to-moderate obstructive sleep apnea.

Detailed Description

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Conditions

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Obstructive Sleep Apnea

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Mild to moderate OSA (5≤ AHI \<30)
* BMI ≤ 45
* Age ≥ 18
* Men \& Women

Exclusion Criteria

* AHI ≥ 30
* BMI \>45
* Current use of steroids or anti-inflammatory medication
* Diagnosis of insulin dependent diabetes
* Diagnosis of autoimmune disorder
* Shiftwork
* Current use of CPAP
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Milton S. Hershey Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Alexandros Vgontzas

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Penn State College of Medicine, Penn State Milton S. Hershey Medical Center

Hershey, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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5218

Identifier Type: -

Identifier Source: org_study_id

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